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Need To Know The Pregnancy First-trimester Urine And Blood Check Up

Posted on 6 days ago

Question: To understand the Pregnacy First-trimester urine and blood check up reports- Question- Our doctor had asked for urine and blood check-up to my wife (HB-Electrophoresis) in which the doctor has explained Elevated A2 value (HbA2 5.2) suggestive of BETA THALASSEMIA TRAIT. Due to which Doctor has suggested an HB-Electrophoresis to me (husband).

Answered by Dr. Vaishalee Punj (15 minutes later)

Brief Answer:
Genetics

Detailed Answer:
Hello,

I have read your query and seen the report as well. From the report it is clear that your wife has Thalassemia trait. It is about carrying the gene for abnormal hemoglobin. It is inherited in autosomal recessive manner. It means that if only one of the two genes is carrying the trait, then it will not produce any clinical features. This is why your wife probably is normal or near normal and didnot know about this before. They may have mild microcytic anemia.
It also means that if you donot carry this gene, then the chances of thalassemia in child are really low. If you have one gene then there would be one in four chances for baby to have thalassemia. So it is good to get yourself tested and get back with reports.

Wish you good health. If you have any specific queries please revert back.
No worries for now.
Regards
Dr Vaishalee

Above answer was peer-reviewed by : Dr. Kampana

Follow up: Dr. Vaishalee Punj (10 hours later)

Thank you so much madam for clearing my doubt. I will surely get the test done for myself.

Answered by Dr. Vaishalee Punj (2 hours later)

Brief Answer:
Thank you

Detailed Answer:
Thanks for consulting me online

Regards
Dr Vaishalee

Above answer was peer-reviewed by : Dr. Vaishalee Punj

Follow up: Dr. Vaishalee Punj (3 days later)

Dear madam, In reference to the ongoing conversation I would like to ask a question as I got tested for HB electrophoresis. And I have my report which interpret - Normal Adult Hemoglobin pattern. Can you please help me to understand both report output of my wife shared earlier and my current report.

Follow up: Dr. Vaishalee Punj (14 minutes later)

Kindly let me know the outcome by referring to both reports and suggest the further step required or not required, is it normal for our baby or suggest the step.

Answered by Dr. Vaishalee Punj (4 hours later)

Brief Answer:
Nothing required

Detailed Answer:
Hi again

Your report is normal, so there are practically no chances that the baby will have thalassemia disease.
There are low chances of thalassemia trait (just like your wife) that may live a normal life. So there is no logic in doing further testing on the baby until born.
Genes sometimes are not simple maths and surprises can happen. But given the current situation, you may relax.

Regards
Dr Vaishalee

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar