No Change After Taking Levetiracetam And Topiramate For Seizures. Suggest The Right Medication

Posted on Fri, 8 Nov 2013

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Fri, 8 Nov 2013 Answered on

Sat, 30 Nov 2013 Last reviewed on

Question : i need to changes the medicine for my daughter.

Answered by Dr. Sudhir Kumar (2 hours later)

Brief Answer: My reply is below. Detailed Answer: Hi, Thank you for posting your query. It is unfortunate that your daughter is having seizures (fits) despite being on four good anti-epileptic drugs (AEDs). The current AEDs- rivotril (clonazepam), zonisep (zonisamide), lametec/lamitor (lamotrigine) and sodium valproate are very effective and safe drugs to control seizures. At this stage, one option is to try other good medications to control her seizures such as levetiracetam and topiramate. Other option is to consider epilepsy surgery. This would require evaluation including MRI brain-epilepsy protocol, video EEG and neuropsychological evaluation. I hope it helps. Please get back if you require any additional information. Wishing you good health, Dr Sudhir Kumar MD (Internal Medicine), DM (Neurology) XXXXXXX Consultant Neurologist Apollo Hospitals, Hyderabad, India Click on this link to ask me a DIRECT QUERY: http://bit.ly/Dr-Sudhir-kumar My BLOG: http://bestneurodoctor.blogspot.in

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Sudhir Kumar (29 minutes later)

Hi Dr XXXXXXX Thanks for the quick response. we have tried this medicine levetiracetam and topiramate previously, there was no control on seizures. then doctor suggested to with draw. please let us know what other medicine can added or removed.

Answered by Dr. Sudhir Kumar (1 minute later)

Brief Answer: My reply is below. Detailed Answer: In that case, I also would like to admit her and evaluate with the MRI brain epilepsy protocol, and long term video EEG monitoring. This would help in deciding to choose the correct medications, and also whether the surgery would be useful or not. Best wishes, Dr Sudhir Kumar MD DM (Neurology)

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Sudhir Kumar (2 days later)

Hi Dr XXXXXXX I am satying in Bangalore. please let us know which hospital will fullfill the needful.

Answered by Dr. Sudhir Kumar (1 hour later)

Brief Answer: Thank you for getting back. Detailed Answer: You can meet Dr XXXXXXX Iyer at XXXXXXX Hospital, Bangalore or Dr XXXXXXX XXXXXXX at Manipal Hospitals, Bangalore. Best wishes, Dr Sudhir Kumar MD DM (Neurology)

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Sudhir Kumar (1 hour later)

Hi Dr XXXXXXX Thanks for the contact detail. i will take it forward. Thanks, XXXX.

Answered by Dr. Sudhir Kumar (7 hours later)

Brief Answer: Thank you Detailed Answer: Thank you and best wishes, Dr Sudhir Kumar MD DM (Neurology)

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar