Normally Taking Amlodipine. Raised The Dosage. Can I Start From Morning?

Posted on Sat, 22 Jun 2013

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Sat, 22 Jun 2013 Answered on

Thu, 11 Jul 2013 Last reviewed on

Question : I normally take 5mg of Amlodipine at 4:15pm daily. The doctor raised dosage to 10mg and wants me to take in the mornings. So I took 10mg today at 4:00pm. Do I start tomorrow morning even though it's been less than 24 hours?

Answered by Dr. Jorge Brenes-Salazar (52 minutes later)

Dear XXXXXXX

thanks for your health concerns. yes, the appropiate thing to do is to start 10 mg tomorrow morning; the medication needs about 5 half lives to reach full effect so in your case that would be within the next 4 or 5 days; it builds up gradually

yours truly

Dr Brenes Salazar MD
Mayo Clinic MN
Cardiology

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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar