Severe Nausea And Vomiting. Have Addison's Disease, On Feeding Tube For Gastroparesis. What Is The Dosage For Intramuscular Levomepromazine?

Posted on Wed, 20 Jun 2012

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Wed, 20 Jun 2012 Answered on

Sun, 15 Jul 2012 Last reviewed on

Question : what is the correct doze of levomepromazine administered intramuscularly. I suffer long term severe nausea and vomiting. I have addisons disease which can be become unstable if my vomiting and nausea is not controlled by this anti-emetic. Also- I am subcutaneous pump administering 20mg hydrocortizone over 24 hours. Also through longterm vomiting and nausea before diagnosis of addisons disease, i have severe gastroparesis and have got a feeding tube for nutrition and do not absorb medicines at all or very well hence need for im injections at home.

Answered by Dr. Anil Grover (1 hour later)

Hi XXXXXXX

Thank you for writing in.
I am a medical specialist with a degree in sub specialty of cardiology.
I read your mail with diligence and shall try to help:

Levomepromazine Anti-emetic dose: Severe Nausea and Vomiting 12.5-25 mg 6-8 hrly. (Severe agitation: Up to 50 mg IM maximum) as bio availability of i/m drug is more hence this is the dose recommended. It is prescription drug and only doctor can prescribe and preferably Visiting Nurse Attendants should be administrating it.

I hope the information is useful. If you have any further question please do write, I wiill be happy to answer.

Best Wishes.

Dr Anil Grover
MBBS, MD (Internal Medicine) DM (Cardiologist)

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar