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Suffer Severe Sleepiness And Fatigue. Taking Warfarin, Digoxin And Paroxetine. Is Bisoprolol Causes Sever Side Effects Of Sleepiness?

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Posted on Sun, 4 Aug 2013
Question: Is bisoprolol noted for severe side-effects of sleepiness? i SUFFER SEVERE SLEEPINESS AND FATIGUE AND IT SEEMS TO BE CONNECTED WITH THE BETA BLOCKER i TAKE IN COMBINATION WITH WARFARIN,DIGOXIN, PERINDOPRIL AND PAROXETINE.
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Answered by Dr. Jorge Brenes-Salazar (7 minutes later)
Dear patient,

Thanks for your concerns. Indeed, lipophilic beta blockers like bisoprolol can have that notorious side effect: insomnia or "unusual dreams", fatigue, lack of energy, loss of libido and sometimes even depression.

Once we encounter that problem in clinical practice, we try to use a hydrophylic beta blocker, such as atenolol (if your kidneys are fine) since this drug does not cross the blood-brain barrier.

I encourage you to discuss this option with your provider.

Truly yours,

Dr Brenes-Salazar MD
Cardiology
Mayo Clinic MN
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Dr. Jorge Brenes-Salazar

Cardiologist

Practicing since :2007

Answered : 1198 Questions

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Suffer Severe Sleepiness And Fatigue. Taking Warfarin, Digoxin And Paroxetine. Is Bisoprolol Causes Sever Side Effects Of Sleepiness?

Dear patient,

Thanks for your concerns. Indeed, lipophilic beta blockers like bisoprolol can have that notorious side effect: insomnia or "unusual dreams", fatigue, lack of energy, loss of libido and sometimes even depression.

Once we encounter that problem in clinical practice, we try to use a hydrophylic beta blocker, such as atenolol (if your kidneys are fine) since this drug does not cross the blood-brain barrier.

I encourage you to discuss this option with your provider.

Truly yours,

Dr Brenes-Salazar MD
Cardiology
Mayo Clinic MN