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Suggest Medical Tests To Rule Out Neurosyphilis

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Posted on Mon, 9 May 2016
Question: What tests should be taken on csf for neurosyphilis
doctor
Answered by Dr. Ajay Panwar (5 hours later)
Brief Answer:
VDRL/Treponemal antibody testing

Detailed Answer:
Hi xxxxxxxxxxx,
Thanks for being on Healthcaremagic.com.
I am Dr.Ajay Panwar, neurologist,here to answer your query.

Firstly, cytological and biochemical examination of CSF may give an indication for neurosyphilis. In a strong clinical suspicion , if a person's CSF shows more than 20 cells and elevated proteins, then it becomes an indication that we should go ahead for further testing for neurosyphilis.

Further, VDRL and treponemal antibodies testing should be done in CSF. Essentially, negative treponemal antibodies will rule out the disease.Though,it has been proven , that tests may come negative,in some rare situations-so,strong clinical suspicion is what matters a lot.

Hope this helps.If you have some further questions,I shall be glad to have you in follow-up.

Regards
Dr.Ajay Panwar,
MD,DM(Neurology)
Above answer was peer-reviewed by : Dr. Arnab Banerjee
doctor
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Follow up: Dr. Ajay Panwar (5 hours later)
My doctor tested the csf for.
VDRL.
Cell count
Protiens
Glucose.
Do you think that is enough to prove no syphilis?
I was told the FTA-ABS blood test should always show positive/reactive in persons infected even if they were treated. Is this true?
doctor
Answered by Dr. Ajay Panwar (10 hours later)
Brief Answer:
Yes.It remains positive in blood even after treatment.

Detailed Answer:
Hi xxxxxxxxxxxx,
Thanks for being in follow-up.

VDRL,Cells,Proteins and Glucose being normal essentially rules out neurosyphilis.However,FTA-ABS test may be conducted in CSF for further evidence.

Yes.Its true that FTA-ABS remains positive even after adequate treatment of Syphilis infection.

Hope that I have answered your query.If you have some further questions,I shall be glad to answer else please close the thread,rate it and write a review.

Regards
Dr.Ajay Panwar,
MD,DM(Neurology)
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Ajay Panwar

Neurologist

Practicing since :2007

Answered : 1827 Questions

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Suggest Medical Tests To Rule Out Neurosyphilis

Brief Answer: VDRL/Treponemal antibody testing Detailed Answer: Hi xxxxxxxxxxx, Thanks for being on Healthcaremagic.com. I am Dr.Ajay Panwar, neurologist,here to answer your query. Firstly, cytological and biochemical examination of CSF may give an indication for neurosyphilis. In a strong clinical suspicion , if a person's CSF shows more than 20 cells and elevated proteins, then it becomes an indication that we should go ahead for further testing for neurosyphilis. Further, VDRL and treponemal antibodies testing should be done in CSF. Essentially, negative treponemal antibodies will rule out the disease.Though,it has been proven , that tests may come negative,in some rare situations-so,strong clinical suspicion is what matters a lot. Hope this helps.If you have some further questions,I shall be glad to have you in follow-up. Regards Dr.Ajay Panwar, MD,DM(Neurology)