Suggest Medicines That Are Affected By Drinking Grape Juice

Posted on Thu, 5 Jun 2014

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Thu, 5 Jun 2014 Answered on

Wed, 25 Jun 2014 Last reviewed on

Question : ARE ANY OF THESE MEDICINES Affected by eATING OR DRINKING GRAPEFRUIT JUICE? SERTRALINE, LEVOTHYROXINR\E, SIMVASTATIN, DIGHOXOINE

Answered by Dr. Dr. Ivan Romich (30 minutes later)

Brief Answer:
hi and welcome to hcm.

Detailed Answer:
Thanks fir the query.
Yes, simvastatin,levotiroxine and sertraline are affected by grapefruit since these drugs are metabolised by citocrom oxidase in liver. grapefruit will inhibit this enzyme so concentration of these drugs in blood will be affected too. however it shouldnt cause serious side effects,but it will reduce drugs efficiency. Since you take 3 drugs i suggest not to intake grapefruit. Wish you good health. Regards

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar