Suggest Remedy For Diarrhea, Nausea And Vomiting When On Linzess

Posted on Tue, 3 Mar 2015

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Tue, 3 Mar 2015 Answered on

Tue, 24 Mar 2015 Last reviewed on

Question : I just took linzess for the first time at about 4:30pm, since then i ham having severe diarrhea, nausea and vomiting. If i try to drink anything it just comes right back out. Are these side effects normal?

Answered by Dr. Dr. Michelle Gibson (58 minutes later)

Brief Answer:
these are possible side effects

Detailed Answer:
HI, thanks for using healthcare magic

Linzess (linaclotide) is used for the treatment of irritable bowel syndrome with constipation.

It causes the release of electrolytes, chloride and bicarbonate, into the intestines and also speeds up the transit time in the bowel (makes the intestinal contents come out faster- possible diarrhea)

Diarrhea can occur in 16 to 20% of persons who use this medication- approximately 1 in 5 persons.
Vomiting is less common- 1 to 2% but can still occur.

This means that it is definitely possible that the medication is responsible for the symptoms that you are experiencing.

I hope this helps, feel free to ask any other questions

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar