Suggest The Ideal Dosage For Hydrochlorothiazide Taken For Muscle Pain

Posted on Thu, 11 Feb 2016

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Thu, 11 Feb 2016 Answered on

Wed, 30 Mar 2016 Last reviewed on

Question : Hi, would like to know if it would be safe to cut my spectral in half in morning and increase hydrochlorothiazide to 25 mg right now it is at 12.5 mg .taking spectral 100 mg twice a day and Norvasc 10 mg once a day as well as synthroid 0.075.my bp is running about 110 /66.to 128 /78 pulse in 60 to 68.the raeson I'm asking very tired swelling in ankles and feet if trying to do everyday life and been having weakness and muscle pain in lower back weakness is more in upper back when moving around. have only been on spectral about two months abd Norvasc three weeks. use to be on altace 10 mg twice aday and hydrochlorothiazide 12.5 once a day but bp was running about 187 over 96 and sometimes spiked to 220 120 .

Answered by Dr. Dr. Meriton Siqeca (1 hour later)

Brief Answer:
My answer is as follows

Detailed Answer:
Hello. Welcome to HCM and thank you for your question. I carefully read your query.

Yes, you may halve the dosage of the 100 mg of that drug, and you can increase Hydrochlorthiazid to 25 mg a day. If your problem is the swelling on your ankles, then it is a well-known side effect of amlodipin (Norvasc). I would recommend you to remove amlodipin from the therapy and restore ramipril (Altace) on your therapy, so the ankle swelling will go away. Since the effect of anti-hypertensive drugs sometimes take 7-14 days to reach their plateau, there may be some fluctuations of your blood pressure figures at first, but my opinion is that your blood pressure figures will soon be returned to controlled and normal. Above all this, I would recommend you to consult your curing doctor about these changes. One thing is for sure, ankle swelling is a well-known, not rare, side effect of amlodipin.

I hope I was of help. I am happy to help, if you have follow-up questions.

Best regards,
Dr. Meriton

Above answer was peer-reviewed by : Dr. Vaishalee Punj

Follow up: Dr. Dr. Meriton Siqeca (6 hours later)

You can stop amlodipin all at once and take Altace 10 mg once a day and sectral twice a day?

Answered by Dr. Dr. Meriton Siqeca (9 minutes later)

Brief Answer:
Welcome back

Detailed Answer:
Hello again.

Yes. It is safe to take combined acebutolol, ramipril and hydrochlorthiazid to control hypertension, and to keep it on the figures we want to achieve. Swollen ankles will be avoided with discontinuation of amlodipin. It is safe and highly effective to combine a beta-blocker with an angiotensinogen converting enzyme inhibitor (ACE-i: ramipril) to "fight" hypertension.

I hope this is helpful.

Kind regards,
Dr. Meriton

Above answer was peer-reviewed by : Dr. Arnab Banerjee