Suggest Treatment For F4 Fibrosis

Brief Answer: XXXXXXX with Obesity is the cause of F4 Fibrosis...in your case!!

Detailed Answer:
Brief Ans-NASH with Obesity is the cause of F4 Fibrosis...in your case !!

Hi Dear!! Thanks for the query to HCM.
Read and reviewed your facts.
Yes the overweight is causing Non-Alcoholic-Steatohepatitis in you.

You can cure it with - following plan-

Regular Exercises
Dietary Strict Control-with high fiber diet
Lipid lowering drugs like Statins-and ezetimibe -reducing abnormal lipids
Pentoxyphylline
Vit E , both have been shown to reduce fibrosis.
Sunitinib
Bariatric Surgery -like Gastric Bypass to reduce the intake effects.
Correction of diabetes if any.
F4 Fibrosis is the initial stage of Cirrhosis of Liver.

Hope this would help you to resolve your worries and plan further treatment with your doctors there.

Welcome for any further query in this regard.

Good Day!!

Dr.Savaskar M.N. XXXXXXX Surgical Specialist
M.S.Genl-CVTS

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Brief Answer:
Don't Worry Be Cautious. Its Compensated XXXXXXX still...!!

Detailed Answer:

Hi Dear !! Thanks for the updated queries from you.
Please find replies for all your queries below.
My Suggestion-
Don't be anxious and don't be neurotic with obsession of death. If taken care you still can have good quality life with right kind of treatment at right stage.
I would try to help you out in taking decisions with your doctors for the best possible health care in time to come.

Q-1. Can this be reversed or is it a death sentence now ?
Ans. If taken care as per suggested plan, you can come out, but it all depends on how much serious and meticulous in caring yourself with the best possible expertise from my side and doctors there attending to YOU.

Q-2. I mean can I have normal liver again if I loose weight?
Ans YES,You can very well have Normal Liver to a great extent, if you lose your body weight.
But here your body mechanisms are at faults.
De novo lipogenesis is more in your case by your internal mechanism.Also de novo burning of fatty acids is also at fault.
So you would require to be attended from expert doctors to guide you about weight loss. You may need Gastric Bypass Surgery to save your liver from this Cirrhotic condition,which is still not complicated with more complications.So you have Compensated liver Cirrhosis, which could be saved by reversal therapies, which are available currently.

Q-3. Is it going to show its effects eventually ?
Ans-Its your good luck, that you could detect it when its still recoverable,as your XXXXXXX is Compensated and is without complications of failed liver function.
If you are meticulous and caring you could come out successfully.

Q-2-iv-What is the difference between fibrosis and cirrhosis ?
Ans-2-iv-Dear, fibrosis is a natural healing reaction to any inflammatory or traumatic injury from any chemical.Here in XXXXXXX the overlipogenesis, induces and inflicts inflammatory damage to liver cells,which detoxicate your blood.
In reaction to this inflammatory damage to liver cells,fibrotic mechanism sets in and goes haywire and uncontrolled, to the extent that it complicates the detoxifying capacity of liver functions,which is yet to happen in your case.
F4 fibrosis- by itself means the fibrotic element is more than required and indicates Compensated Cirrhosis or subclinical liver disease, without any complaints,as the liver function is still not deranged to that extent.

Q-3-i-Also should I get any other test to confirm f4 fibrosis ?

Ans-3-i-I would suggest you to leave this to Me and your attending doctors to take care of. We will do every care possible to save you out of this dreaded disease.
What is important is to accept at your level and co-operate for its treatment right after here, without wasting more time at hand.
There are many tests and there are many indications to do it.
you have already done- few like fibroscan and Transient Elastography with Kpa 17, which is almost 2 times normal upper limits./ your sgpt is raised but still under acceptable abnormal upper limits.
So all these tests suggest- a yellow signal which is going to convert in to red if you don't CARE it.
There are many non-invasive biomarker test to assess the extent of fibrosis, which is a subject of Cost and its effectivity and is to be handled by expert doctors. And I would help you in that in time to come.


Q-3-ii-Can the test be wrong or machine be wrong ?
Ans-3-ii-By no Means,They Can't Go WRONG, as they are assessed from expert doctors there with you.
Gradation and its understanding may vary a bit, but conceptually. You are proven case of XXXXXXX with obesity

Hope this would help you to resolve your worries and plan further treatment with your doctors there.
So don't worry and keep Me updated 24x7 for all the help online.

Welcome for any further query in this regard.

Good Day!!

Dr.Savaskar M.N. XXXXXXX Surgical Specialist
M.S.Genl-CVTS

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Brief Answer:
Don't Worry Consider Updating Me if needed

Detailed Answer:

Hi Dear !! Thanks for your updated but almost repeated queries which have been replied by me.
I understood your concerns. And that's why I have allowed You to keep Me updated
24 x 7, if you need,for you to come out of this problem.
Answer to all your queries is YES, if advice followed strictly you can lead a healthy life.
Hope this resolves all your queries to your satisfaction.

Keep Me updated whenever needed 24 x 7, to help you out by even, online tips for You, on weekly basis.

Welcome for any further query in this regard.

Good Day!!
Dr.Savaskar M.N. XXXXXXX Surgical Specialist
M.S.Genl-CVTS

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Brief Answer:
Alertness reductions is from accompanied Hepatitis from XXXXXXX ..!!

Detailed Answer:
Brief Ans-Alertness reductions is from accompanied Hepatitis from XXXXXXX ..!!

Hi Dear !! Thanks for very inquisitive query.
Read and Reviewed the facts of your last query in context of your lack of Alertness in last 2 weeks.
In My opinion and based on your latest LFT and Renal profile Tests- You have marginal liver function stress with rise in ALT (SGPT).
I would suggest to avoid fatty meals and high protein diet currently.
You should have high carbo and liquid diets mostly.
Avoid cheese and milk products during this period for 3 weeks.
Less of spices / more of fluids and glucose supplements to over come low glycogen stores, which are depleted due to liver cells injuries.

Q-1-I am feeling little lack of alertness since last two weeks that too sometimes

Ans-1-Lack of alertness and Weakness for last 2 weeks, is from low glycogen reserves, which needs to be recouped by high carbo diets and

Q-2-Can be because of anxiety or liver ?

Ans-2-Excess Anxiety and stress, also causes discharge of body energy from high sympathetic activity and leading to low sugar reserves in body.

-Remedy Suggested-
Rest- for 8-10 hrs for next 2-3 weeks time.
Sugar Cane juice supplement / or Glucon C supplements to recoup ,
Vit E 400 mg 1 x 2 times a day
Tab Zincovit 1 x 1 per day.
Rice Soups with sugar x 3 times a day.
Should be the treatment for next 3 weeks.

Q-3-I also read about hepatic encephalopathy I hope I don't have that?

Ans-3-Dont be obsessive and hypochondriac.don't increase body stress from anxiety and neurosis.

Q-4-My urea level in urine is ok
Should I have ammonia test ?

Ans-4-The damage is not severe to call for Blood ammonia.You don't have the weakness / lack of alertness and by no means from encephalopathy.

Q-5-Also I m uploading my reports of liver function test and kidney test

Ans-5-Liver is marginally stressed and could recover with treatment suggested above.Get back to Me every 3 rd day with your briefing on your progress, every Monday and Thuseday by a direct private question to ME.

Hope this would help you to come out of the anxiety neurosis and obsession of death from F4 fibrosis , which is early Cirrhosis with no complaints- meaning its Compensated XXXXXXX still.

Please review my profile on tissue failure therapies.Do revert to ME on my mail YYYY@YYYY for any further care.

Welcome for any further query in this regard.

Dr.Savaskar M.N. XXXXXXX Surgical Specialist
M.S.Genl-CVTS

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