
Suggest Treatment For Allergic Reaction To Fentanyl Drug

hi, rare type problem
Detailed Answer:
Hi, this form of delayed allergic reaction which is usually rare to be seen. In case of opioid like fentanyl it is seen only when it is given into fluid around brain and spinal cord. This type of problem usually occurs due to something called mu receptor in the body and is short lasting say 2-3 hrs treated well by inj propofol 20 mg or so. Bit if it is so delayed as to few days you shall talk to the converned doc and you may require opiod antagonist that acts on mu receptor. Such a drug available is Nalaxone. This s administered in a hospital setup under strict supervision and may have to repeated 4-5 times.


no EEG wont tell about receptors
Detailed Answer:
Hi,
Never heard of fentanyl lingering on in the body for so long. XXXXXXX of 96 hrs or 4 days. But your case may be an exception, but never heard of.
EEG would only tell if there is any problem with the brain that is causing her to itch her face. It does not tell about receptor. Doctors might be suspecting it to be part of some kind of epileptic focus.
You can discuss about my opinion with the treating doctor. We can discuss further.


Not sure if I mentioned that when she was returned to her room to recover from anesthesia/scope, they said she would awake in 5 or 10 minutes, she did not awake for the full 2 hours afterwards, thrashing and crying out about the itch but eyes closed the entire time, hyperventilating etc. After several hours, with no medications helping, the anesthesiologist opened her eyes with his hand (I saw her eyes rolled back in her head as I was trying to comfort her), when he did this with one eye they both popped open immediately and she was wide eyed and went from hyperventilation to a sudden stop…then normal breathing, wondering why there were so many doctors and nurses at her bedside. She does not recall the incident at all.
Also, she is adopted, we don't know much about her family history except that there was drug addiction from before she was born. Could this somehow be a factor with the opiate?
good she s better
Detailed Answer:
Hi, usually this type of events happen post anesthesia. Uncommon but not rare. Its very normal to not remember such events under the effects of anesthetic agents.
Her drug addict parental history shall not be a factor here.
H.pylori may be a reson for this and if this is in the documented report, better to start with Metronidazole/ciprofloxacin combination. These are antibiotics and you shall get prescription from your gastroenterologist.

Answered by

Dr. Rohit Gulati
Pain Medicine & Palliative Care Specialist
Practicing since :1999
Answered : 252 Questions
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