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Suggest Treatment For Cholesteatoma Other Than Surgery

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Posted on Wed, 11 Feb 2015
Question: Dr. XXXXXXX
I am a disabled XXXXXXX with cholesteatoma. For several
reasons I am NOT a good candidate
for surgery. Are there any new
non-surgical options other than
microsuction you are aware of
or new less evasive treatments?
Thank you.
doctor
Answered by Dr. Sumit Bhatti (2 hours later)
Brief Answer:
First confirm the cholesteatoma.

Detailed Answer:
Hi,

Thank you for your query.

1. Having gone through all your previous questions and scan reports on this condition, I recommend that you undergo an MRI for Cholesteatoma (a new protocol published as a co-author): http://www.ncbi.nlm.nih.gov/pmc/articles/PMC0000/
along with an HRCT Temporal Bones. This would give the most accurate evaluation of your ear condition.

2. From your current scans, your Right Ear has minimal disease, easily managed by meticulous cleaning and regular follow-up. Your Left Ear seems to have a larger extent of disease.

3. Cholesteatoma is a destructive, aggressive but slow disease while your scans show that the ear, ossicles and temporal bones are intact. This goes against a cholesteatoma and more in favor of retraction pockets which can be manged non-surgically. CT and non-contrast MRI cannot differentiate between cholesteatoma and other ear conditions, hence the recommendation for the above.

4. The nature of cholesteatoma requires surgical management. There is no established non-surgical management except for retraction pockets and quiescent disease such as where dry ear, no discharge or flakes are seen. Ear discharge in cases of cholesteatoma is always scanty, intermittent and hence a dry ear may give a false sense of security while it spreads inside the temporal bone.

5. Interestingly, an ear drum perforation will arrest the development of an early cholesteatoma.

6. If you can upload images of these new scans (not the reports), a PTA (Pure Tone Audiogram) and video-endoscope ear drum images (Left and Right Ear), I will be able to give you an accurate assessment.

I hope that I have answered your query. If you have any more questions I will be available to answer them.

Regards.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Sumit Bhatti (5 hours later)
Dr. Bhatti,
God bless your very detailed response!
There is a time difference here and I just woke up.
I shall reply as I am able now as I work today and I will gather
anything I do have and see if I can get more from
previous tests. This will take several days as there
is one Medical Report from a visit about 3-4 months
ago I do not have.
Here's where the challenge comes in. I have several
brain MRI's since 2000 that indicates a possible problem in
the Mastoid area but no doctor ever looked into. The
2011 MRI states on it "Correlation is recommended" but
the attending doctor did not look further into. I did have
alot of earaches and antibiotics as a child. So it does not
look I've caught this in the early stages. However, I am
keeping the situation under control via natural means but
most do this morning and night to avoid symptoms.
The hearing loss has not progressed as
long as I do this. Surgery not an option for me due to
my history which you have now read.
I am touched by the depth of your insight and ask
that you bear with me as I, in slow time, gather and
send your information. I do not have a ENT here, at
the present time, that I can rely that is forthcoming.
Thank you.
doctor
Answered by Dr. Sumit Bhatti (4 hours later)
Brief Answer:
You may follow up here or directly at bit.ly/Dr-Sumit-Bhatti

Detailed Answer:
Hi,

Thank you for writing back.

1. You may follow up here or directly at bit.ly/Dr-Sumit-Bhatti when you have more information to discuss.

2. These MRI protocols for Cholesteatoma were developed post 2010 and are still not in mainstream use.

3. A 'cholesteatoma hearer' is a patient who does not exhibit hearing loss even after ear ossicle destruction as the cholesteatoma sac and matrix bridges the gap.

Awaiting your reply,

Regards.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Sumit Bhatti (27 minutes later)
Dr. Bhatti,

Thank you for your reply.
Off to work.
Will gather info and send slowly, do you
want prior brain MRI's (5 or 6)?
I'm very grateful for your help and competence.

doctor
Answered by Dr. Sumit Bhatti (4 minutes later)
Brief Answer:
Yes, you may gather the info. I would prefer the latest scan as above.

Detailed Answer:
Hi,

Thank you for writing back.

1. Yes, I would prefer to review the the images instead of the reports.

2. You may need a file sharing site for large volume data.

3. I would expect the latest or any future scan as above.

I hope that I have answered your query. If you have any more questions I will be available to answer them.

Regards.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Sumit Bhatti (18 hours later)
Dr. Bhatti,
I don't recall what was sent to the previous healthcaremagic
doctor there so I will send all I have in the past six months.
Again, I'm involved in a large project from work so it will be
awhile before I can send.
Do you believe its possible to keep a cholesteatoma from
growing and manage symptoms by addressing infection
and inflammation as I am doing?
Thank you!
doctor
Answered by Dr. Sumit Bhatti (8 hours later)
Brief Answer:
Follow up: bit.ly/Dr-Sumit-Bhatti. Early, shallow disease can be controlled

Detailed Answer:
Hi,

Thank you for writing back.

1. You may have to follow up directly at bit.ly/Dr-Sumit-Bhatti if there is a delay.

2. An early or a shallow cholesteatoma can be slowed down by careful suction clearance and controlling infection and inflammation. The cleaning of the cholesteatoma sac is of greater importance. It does help to control infection and inflammation as proteolytic enzymes help it spread. However the cholesteatoma contains dead desquamated cells and debris outside the body where the medication will not penetrate easily. A large cholesteatoma or a cholesteatoma sac with a narrow mouth will require surgical management.

I hope that I have answered your query. If you have any more questions I will be available to answer them.

Regards.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Sumit Bhatti (2 hours later)
Dr. Bhatti,
Thank you sincerely for your reply.
I was able to just now obtain the November, 2014 Medical Report
which I am now attaching. Regarding the current CT Scan I have
it is in Read Only format. I have a call into the imaging center
to see if I can obtain one I can send to you with images.
I believe you already have the other three ENT surgeon notes, yes?
Would having a perforated eardrum be contradindicated for the
microsuction as it did make it much worse. Options?
If you know or hear of any options for a situation like mine
non-surgically, it would be most appreciated.
I am grateful for your review :)
doctor
Answered by Dr. Sumit Bhatti (8 hours later)
Brief Answer:
Report not accurate. Previous reports N/A. Perf no problem. Rt ok, Left?

Detailed Answer:
Hi,

Thank you for writing back.

1. Surprisingly, your November 2014 Medical Report does not mention any ear drum perforation in the local ear findings, while it is mentioned in the diagnosis and summary. The tuning fork tests are shown as normal, which is not expected with your audiogram findings.

2. No, I have not seen the previous three ENT reports. Kindly upload them along with a latest Audiogram.

3. An ear drum perforation is not a contraindication for ear microsuction and a carefully done gentle suction clearance will not make it worse.

4. Your right ear seems to be of no problem with conservative management. The left ear is where a doubt exists about the extent of the attic retraction and whether it is an active cholesteatoma. If you can follow my earlier imaging guidelines, we can arrive at a definitive conclusion.

I hope that I have answered your query. If you have any more questions I will be available to answer them.

Regards.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Sumit Bhatti (6 hours later)
Dr. Bhatti,
I am grateful for your reply and straight answers.
Honest help from around the world. God is looking down on
me :)
I have not heard back from the imaging center regarding
getting a new CD, other than Read Only one I have, for the recent CT scan.
This morning again I am getting ready for work and shall
have to send you your requested downloads later.
The night before I went to the first ENT the infection had
gotten so bad the eardrum burst. Isn't that the same as
a perforated eardrum? That's what I called it.
I wish the ENT doctors I have been in contact with at Healthcare
Magic practiced in my country. Your level of straightforwardness
refreshing. The only way medicine should be practiced. You give
dignity back to your profession and the Hippocratic Oath, "Doctor
do no Harm".
Thank you!
doctor
Answered by Dr. Sumit Bhatti (7 hours later)
Brief Answer:
Burst eardrum = perforated eardrum.

Detailed Answer:
Hi,

Thank you for your kind words.

1. A burst eardrum is the same as a perforated eardrum.

2. The incidence of large cholesteatomas is falling as there is more awareness of this disease. Early intervention in childhood Eustachian tube dysfunction has reduced the incidence of cholesteatoma as compared to 2-3 decades ago.

3. Upload whatever images you can for now while you wait to gather the rest.

I hope that I have answered your query. If you have any more questions I will be available to answer them.

Regards.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Sumit Bhatti (2 hours later)
Thank you for your reply, Dr. Bhatti and answer.

I have gathered my current information and tried to
download these (Medical Reports and
MRI's) to this site several times but the downloads
do not show above on this page as being received.



doctor
Answered by Dr. Sumit Bhatti (8 hours later)
Brief Answer:
Please contact YYYY@YYYY or call at the nos below:

Detailed Answer:
Hi,

Thank you for writing back.

1. There are no recent uploads visible.

2. The previously uploaded 'November 2014 Medical Report' is also no longer visible.

3. If the file sizes are large, kindly contact
E-mail YYYY@YYYY or Call: USA: +1-718-340-3660, India: +91-80-4190-3696 for further assistance.

Awaiting your reply,

Regards.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Sumit Bhatti (4 hours later)
Dr. Bhatti,
Thank you for your reply.
Per your request, all available information
just downloaded to your customer care
website for forwarding to you.
Kind regards.
doctor
Answered by Dr. Sumit Bhatti (7 minutes later)
Brief Answer:
I will look into it. Thanks.

Detailed Answer:
Hi,

Thank you for writing back.

I will review the information when it is forwarded to me via HeakthcareMagic.com

Regards.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Sumit Bhatti (1 hour later)
Dr. Bhatti,
Regardless of how you answer my situtation
after you have reviewed my reports, I will
give you an excellent rating !!!!!!!!!!
My situtation should have been brought to
my attention when it was first showing up
on MRI's in 2000 when it was more
treatable. I am keenly aware of this.
Please know I understand.
You have given me great answers in
previous emails :)
Kind regards.
doctor
Answered by Dr. Sumit Bhatti (6 hours later)
Brief Answer:
Please confirm that HCM has received your submitted data.

Detailed Answer:
Hi,

Thank you for writing back.

1. I have not received any forwarded information yet. Kindly check with the HealthcareMagic (HCM) support team. I will also check with them tomorrow.

2. I will not be able to answer unless you post a follow-up query as the option of answering is only available at that time and then on for about 24 hours.

I hope that I have answered your query. If you have any more questions I will be available to answer them.

Regards.
Above answer was peer-reviewed by : Dr. Vinay Bhardwaj
doctor
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Follow up: Dr. Sumit Bhatti (1 hour later)
Dr. Bhatti,
I did just speak with the healthcaremagic support and
they said to foward to another email address. I just did and
I hope you now receive the downloads.
Let me know if you do.
Thank you.
doctor
Answered by Dr. Sumit Bhatti (15 hours later)
Brief Answer:
There is no evidence of cholesteatoma. Proceed with imaging.

Detailed Answer:
Hi,

Thank you for writing back.

1. I have gone through all the attached reports. There is no evidence of any choleateatoma either on the clinical findings (dry central perforation on the left) or on any of the scan reports (chronic mastoiditis is reported consistently).

2. Cholesteatoma cause bone destruction and the delicate air cell partitions in the mastoid are broken down, There is no mention of similar benign condition of sevre mastoiditis known as coalescent mastoiditis either which can cause the suspicion of a cholesteatoma. If you can attach some images, it would help.

3. On direct examination and microscopy, an active cholesteatoma will reveal a foul smelling ear discharge with a distinctive 'fishy' odour. There will be epidermal flakes and granulation tissue (suggestive of osteitis).

4. To put an end to all this speculation, proceed with the MRI for Cholesteatoma + HRCT Temporal Bones and not a PET Scan as advised. A good clinical examination or oto-endoscopic pictures will also clear this issue without a reasonable doubt. This scanning protocol will clear 100% of the doubt.

5. The other findings such as the tectal lipoma and the chiari malformation are constant without change (stable). That is good news.

6. There is no contraindication for treatment of cholesteatoma. A cholesteatoma can also be operated under local anesthesia as is done commonly in XXXXXXX

I hope that I have answered your query. If you have any more questions I will be available to answer them.

Regards.
Above answer was peer-reviewed by : Dr. Bhagyalaxmi Nalaparaju
doctor
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Follow up: Dr. Sumit Bhatti (24 minutes later)
God bless you, Dr. Bhatti:
It is good to hear this news.

* I do have photos taken by the first doctor I will try to scan clearly
and send to you.
* I was told they use general anesthesia and some general anesthesia.
* Still waiting to hear back from imaging center.
* Have contacted first ENT. Waiting to hear back for appt.
* Will download photos to same address I just sent previous downloads.
* Will also advise further history details to that same address.
* There was that foul smell on the day the eardrum burst. However,
since then (10/14) I have daily addressed infection and inflammation
issues via natural means and the ear has remained dry.

I am very grateful for your patience and hope I have not caused you
any inconvenience.
*Correction to above: ENT said they use a general with some
local anesthesia but that they have to
use predominantly general anesthesia.
* Have color photos of before and after Ciprodex drops but unable
to get good images from my printer. Will take to a copy center
today. ENT recommended a CT scan at the time of photos/exam to determine
whether I had an actual cholesteatoma which he did confirm
after the CT. All four ENT's wanted to do c-toma surgery.
* If I don't have a cholesteatoma, is it possible to avoid surgery for the
perforated eardrum and retracted eardrum, mastoiditis situation.
With enormous gratitude.......

With sincere appreciation!
doctor
Answered by Dr. Sumit Bhatti (36 minutes later)
Brief Answer:
Your ear disease seems to be stable.

Detailed Answer:
Hi,

Thank you for writing back.

1. It will be useful to review any scan images you can locate.

2. Ear operations are routinely done under local anesthesia and sedation. In apprehensive or very young patients, general anesthesia is used. There is less bleeding under local anesthesia (and hence a good operative field), hearing can be tested on the OT table among other benefits.

3. A smell and ear discharge on the day the ear drum burst is normal. Other wise your ear perforation is dry. As I have mentioned before, a ear perforation arrests the spread and development of a cholesteatoma (if it exists).

I hope that I have answered your query. If you have any more questions I will be available to answer them.

Regards.
Note: Consult an experienced Otolaryngologist / ENT Specialist online for further follow up on ear, nose, and throat issues - Book a Call now.

Above answer was peer-reviewed by : Dr. Bhagyalaxmi Nalaparaju
doctor
Answered by
Dr.
Dr. Sumit Bhatti

Otolaryngologist / ENT Specialist

Practicing since :1991

Answered : 2686 Questions

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Suggest Treatment For Cholesteatoma Other Than Surgery

Brief Answer: First confirm the cholesteatoma. Detailed Answer: Hi, Thank you for your query. 1. Having gone through all your previous questions and scan reports on this condition, I recommend that you undergo an MRI for Cholesteatoma (a new protocol published as a co-author): http://www.ncbi.nlm.nih.gov/pmc/articles/PMC0000/ along with an HRCT Temporal Bones. This would give the most accurate evaluation of your ear condition. 2. From your current scans, your Right Ear has minimal disease, easily managed by meticulous cleaning and regular follow-up. Your Left Ear seems to have a larger extent of disease. 3. Cholesteatoma is a destructive, aggressive but slow disease while your scans show that the ear, ossicles and temporal bones are intact. This goes against a cholesteatoma and more in favor of retraction pockets which can be manged non-surgically. CT and non-contrast MRI cannot differentiate between cholesteatoma and other ear conditions, hence the recommendation for the above. 4. The nature of cholesteatoma requires surgical management. There is no established non-surgical management except for retraction pockets and quiescent disease such as where dry ear, no discharge or flakes are seen. Ear discharge in cases of cholesteatoma is always scanty, intermittent and hence a dry ear may give a false sense of security while it spreads inside the temporal bone. 5. Interestingly, an ear drum perforation will arrest the development of an early cholesteatoma. 6. If you can upload images of these new scans (not the reports), a PTA (Pure Tone Audiogram) and video-endoscope ear drum images (Left and Right Ear), I will be able to give you an accurate assessment. I hope that I have answered your query. If you have any more questions I will be available to answer them. Regards.