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Suggest Treatment For Hiatal Hernia And Mild Inflammation Gastritis

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Posted on Wed, 30 Sep 2015
Question: Hi,

Im really worried. I just did a full blood test as i am tired and really really stressed at the moment. I did an endoscopy and i have hiatal hernia, mild inflammation gastritis and in the dudodem. They dont think its celiac. So my blood work is all fine except the abs. Cd8 - cd57 plus lymphs is low at 56 the range is 60 to 360. I dont have lyme nor hiv and all my blood was fine. Im so worried should i do auto immune tests now?
Two years ago i saw a rheumatologist after i got a positive ana test but she said it went negative and all the tests she did were fine. She said it may have been positive because auto immune is in my family. I also have excema and psoriosis in my head. Thanks
doctor
Answered by Dr. Naval Mendiratta (1 hour later)
Brief Answer:
Autoimmune problem

Detailed Answer:
Good evening

Thank you for writing on health care magic

Well your CD 8 is marginally low but it not something very alarming. So firstly I would like to ask you to take it easy. CD 8 normally is not so significant for autoimmune disorders. It is the ratio of CD4: CD8 which is more significant.

I understand your ANA was positive 2 years ago. I would like to ask you a few more queries just to be sure the autoimmune disease has not evolved any further:

1. How bad is your fatigue? Is it there all the time or you feel better on waking up?

2. Any history of oral ulcers/joint pains/hair fall/rashes/photosenstivity?

3. What other autoimmune disorders are present in your family?

4. Any history of forgetfulness/disturbed sleep/irritability?

5. How strong were the ANA titres?

6. Any complaints of dry eyes or dry mouth?

7. Were your other results ok...that is the CBC, Differential count, ESR?

Do let me know these queries. Would try to sort it out for you if you need any further tests

AWait your reply

REgards
Dr Naval
Above answer was peer-reviewed by : Dr. Neel Kudchadkar
doctor
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Follow up: Dr. Naval Mendiratta (1 hour later)
I don't think they did the esr yet. The CBC was all normal . I am just tired and have anxiety. I have not had any rash. The Ana two years ago was 1.8o the lowest one. My sister has rheumatoid arthritis and my grandmother had pernicious anemia. The rheumatoid two years ago did all the tests and they came back negative that's all I know. I probably need to do the esr now right? I'm so nervous what could have caused this? The only one that is not right is this abs cd8 cd57 + lymphs is 56 the other one the %cd8 cd57 + lymphs is normal at 4.3 % WBC is 4.6 I don't know where to see the differentials on the form. My hair falls out a little yes from time to time. My thyroid is normal. I'm tired all of the time but I am stressed too.
doctor
Answered by Dr. Naval Mendiratta (19 hours later)
Brief Answer:
Autoimmune Disease

Detailed Answer:
Good evening

Sorry for the late reply. Had a long duty on Sunday

Well, I dont think you need to be worried about the CD 57 Lymphocytes as some people do have a very low count without any symptoms. I am still not sure why it was measured as it is very specific for Lyme disease. Since your WBC is also good, nothing too be worried about.

If you do a whole body check up , lot of times lab gives abnormality as those are machine values which may not be too significant but tends to scare the patients.

Never the less, If you want I can advise you certain tests just to be sure it is not an autoimmune condition cause you are under lot of stress. If the test results show any abnormality you can consult a rheumatologist, or else you should be good.

Kindly do:

1. Repeat ANA
2. ENA profile
3. ESR
4. Rheumatoid Factor
5. 25 hydroxy vitamin D3 levels
6. Check for your CD4 levels if it has been done

This will cover the autoimmune spectrum and give us the final answer

Just try to relax, go out and have a good weekend

Do let me know for more queries

Regards
DR Naval
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Naval Mendiratta (3 hours later)
Ok thank you. Im so worried because last time i had a positive ana but low but when they did it again it was negative and so were the other tests. What could that have meant back then? They said probably because someone in your family had auto immune. Now with this ive started to panic again.
doctor
Answered by Dr. Naval Mendiratta (9 hours later)
Brief Answer:
ANA positivity

Detailed Answer:
Good morning

Well, if the repeat ANA was positive and then negative then there is probably a faulty technique with the way the test has been done, with either of the labs. ANA is a antibody which when present tends to stay. But it is not always that it causes symptoms

Firstly, your ANA was positive in a very low titre which may not be significant. 5-10 % of normal population has ANA without any symptoms. So if it positive and you dont have any symptoms we tend to ignore it but just keep a regular follow up as we treat the patient. Lab results are only supportive but not conclusive

Secondly, as of now you dont have any symptoms of connective tissue disease. All the questions I asked were pertaining to that. So I dont think you should worry too much. The stress is gonna aggravate all the pain and fatigue, so try to take it easy

Thirdly for your satisfaction, we can get all the tests done( as advised). Even if ANA is mildly positive but the ENA profile is negative, you can then consider yourself in those category who just have ANA positive without any symptoms

I hope the information was useful

Do let me know for more queries

Regards
Dr Naval

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Naval Mendiratta (10 hours later)
Hi, i went to the doctor today and he will test for lyme regarding that result. The thing is i have a virus and it has been going on since last week. Sorerhroat etc. Could that have been cause? So worried
doctor
Answered by Dr. Naval Mendiratta (3 hours later)
Brief Answer:
Viral infection

Detailed Answer:
Good evening

Dont be worried dear

Sore throat probably is due to viral and it may have caused the cells to fluctuate. As mentioned, if the ratio is fine you are good to go. Plus your CD 8 count and TLC is in normal range, which is more specific. So dont be worried. GO have a drink and take it easy

Do some warm saline gargles and take a tyenol for the sore throat. Incase it is persisting take a course of antibiotics

Do let me know how the lyme results go....

Regards
Dr Naval
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Naval Mendiratta (8 days later)
Hi,

Still waiting for those Lyme results but I'm going to my general doctor on Thursday to talk about why I'm so tired. I haven't stopped worrying about the result of 56 for the test. See above cd57/cd8 . On the Internet it says it's low if you have hiv, Lyme etc but no mention of regular viruses!!!! Hiv I have been tested for and I don't sleep around. Lyme ok but I've never had a tick bite ?? What did you mean if the percentage is normal?? Which it was. But can regular viruses just lower the cd 57?? I am so so tired all the time and suffer with adrenal stress and worry too. Please help!! Thank you !
doctor
Answered by Dr. Naval Mendiratta (16 hours later)
Brief Answer:
Role of CD 57

Detailed Answer:
Good evening

Sorry for the delayed reply

Well, the stress factor is causing a lot of tiredness. As such CD 57 does not have much role in the body. It is more of a marker of lyme disease , which you can check if needed but it can still be misleading. The major production is by CD 8 and CD 4 cells , whose levels are normal in your case.

The thing is lot of these tests are of very low significance and all they do is scare the patients. Even if you test for some more of these things, you may find high or low levels which is common in any patient. All these lab results do is create more panic

The ratio is normal, means your cells are in adequate numbers and CD57 alone being low holds no significance. So, I would suggest to ease up on it.

As for the fatigue, it can very well be a part of your stress which can trigger a condition called Fibromyalgia. IF you want you can read up on it. De stressing yourself will help you. I would not want you to start medications for it. Meditation will help you here.

I hope the information was useful

Do let me know for more queries

REgards
Dr Naval

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Naval Mendiratta (6 hours later)
Hi,

I appreciate your help. I guess i am highly anxious. I dont think i had the cd 8 test as you mentioned. I had the cd8/cd57 test( see above) of which came low. So just to clarify... Do you think a virus / sorethroat could have affected this?

Thanks.
doctor
Answered by Dr. Naval Mendiratta (22 hours later)
Brief Answer:
CD 57

Detailed Answer:
Good evening

Sorry for the late reply. Had a long emergency duty

Well, they checked your CD8 in that ratio which is mentioned. SO it would have been normal since cd 57 was low but the ratio was within normal limits.

Some viruses can affect CD 57. Lot of things in our body go unexplained and there is a high chance of a viral infection affecting CD 57 as well.

Although it has been mostly used as a marker for Lyme disease, it is still not sensitive. Or it could have been low from much before. You just happen to check it since you are in a lyme prone area.

Either ways the role of CD 57 in our immunity is negligible compared to CD 4 and CD8 cells which play all the roles of immunity, destroying foreign body and safeguarding us.

I would suggest to repeat if after a couple of months and see if the results are same. But at the same time I dont want you to be under stress for the same. So let the result of lyme disease also come and we will have a clear answer

Regards
Dr Naval
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Naval Mendiratta (29 minutes later)
Oh i see yes. I think i had other cd tests that were normal i have to check. My doctor today who is a general practioner said he would not repeat it as he said it has no significance. I use two doctors and the one who ordered it was a holistic doctor who orders different types of tests. I will get my results and send them to you. I guess i am a worrier and i like to understand cause and explanation. I read so much and i like to know why! The ambiguity causes me terrible adrenal fatigue symptoms. They mentioned cortisol today becAuse i think mine may be low. I crave sugar and salt and feel so so tired!!! So how on earth do i fully understand my low results and be relaxed. ? I will send my blood work over in the next message and will hear about lyme next week. Best, XXXXXXX
doctor
Answered by Dr. Naval Mendiratta (17 hours later)
Brief Answer:
Significance of CD 57 ...????

Detailed Answer:
Good evening XXXXXXX

Well, I guess little faith would help you relax. If anything was alarming, we would have advised you further tests on it. More than you, we would like you to be fit and healthy.

Lot of lab results are ambigous which leaves the patient wondering and confused as they are performed by the machines with no background knowledge of the patient.

I would suggest dont read up on google anymore and just try to calm it out. You can get your cortisol checked but I doubt it would be anything alarming.

Do let me know about the blood tests..

And it s a weekend. Just go out and ease yourself. Forget about the worries for a few hours. You belong to the place of Tomorrowland...Has to be something amazing :)

Regards

Dr Naval
Note: For further follow up on related General & Family Physician Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Naval Mendiratta

Rheumatologist

Practicing since :2007

Answered : 754 Questions

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Suggest Treatment For Hiatal Hernia And Mild Inflammation Gastritis

Brief Answer: Autoimmune problem Detailed Answer: Good evening Thank you for writing on health care magic Well your CD 8 is marginally low but it not something very alarming. So firstly I would like to ask you to take it easy. CD 8 normally is not so significant for autoimmune disorders. It is the ratio of CD4: CD8 which is more significant. I understand your ANA was positive 2 years ago. I would like to ask you a few more queries just to be sure the autoimmune disease has not evolved any further: 1. How bad is your fatigue? Is it there all the time or you feel better on waking up? 2. Any history of oral ulcers/joint pains/hair fall/rashes/photosenstivity? 3. What other autoimmune disorders are present in your family? 4. Any history of forgetfulness/disturbed sleep/irritability? 5. How strong were the ANA titres? 6. Any complaints of dry eyes or dry mouth? 7. Were your other results ok...that is the CBC, Differential count, ESR? Do let me know these queries. Would try to sort it out for you if you need any further tests AWait your reply REgards Dr Naval