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Suggest Treatment For Klebsiella Pneumoniae

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Posted on Wed, 1 Mar 2017
Question: I've been diagnosed with klebsiella pneumoniae from an upper vaginal swab. I am 18 weeks pregnant and terrified that this will affect my baby.
I'm on co/amoxiclav 500mg x 3 daily. I'm in a terrible state.
I've read up on a case where this infection got to the fetal placenta and led to fetal demise.
Please let me know how dangerous this infection is in pregnancy.
I'm worried it will infect the placenta.
Also what if it is not sensitive to the co-Amoxiclav.
This is my third infection in just a few weeks. I had a vaginal infection of strep C and G which was treated with penicillin V and subsequently cleared. I then had a strep A infection on my groin which was treated with fuicidin H and it also cleared. The itching and yellow discharge never stopped and that's why I was retested and this time they found klebsiella pneumoniae on both upper vaginal swab and also on the labia and groin swab. The lab found the upper vaginal klebsiella pneumoniae sensitive to co-amoxiclav hence I am on it. However the lab has not yet confirmed that the klebsiella pneumoniae found in the labia and groin is also sensitive to co-amoxiclav. It has been 5 days since the swab so I am very worried that it is not being treated.
My questions are:
1) how dangerous is an upper vaginal infection of klebsiella pneumoniae?
2) can it cause PPROM?
3) how soon after taking the antibiotics should I be retested. I've been on them for 3 days but still have itching.
4) will I need recurrent testing throughout my pregnancy to make sure it doesn't recur. I am terrified that I may have an asymptotic infection which could cause problems, especially since this is my 3rd vaginal infection in just a few weeks.
5) is it safe to take probiotic supplement tablets containing live cultures to try and prevent future infections and to correct the vaginal balance.
6) in order for a vaginal infection to cause PROM does it have to have been festering for a long time and would I have to be very sick or could this just happen suddenly without serious symptoms?
Please help.
doctor
Answered by Dr. Purushottam Neurgaonkar (8 hours later)
Brief Answer:
Pesonal hygiene. Antibiotics, antifungals, uterine relaxants,CRP

Detailed Answer:
Hi there.
I have understood your concern.

Firstofall do not panic.

Please get culture ans sensitivity report of the vaginal swab done.

I will suggest you to continue with your current antibiotic treatment for 7 days.
Use of local antibacterial and antifungal vaginal pessaries for 7 days will be of help.
Also, a suitable oral antifungal is advisable.
I will suggest regular use of Lactic acid containingvaginal wash at bath time.
Use of pre probiotics containing spore forms is advisable.

I will suggest you to seek prescription help from your treating doctor for the same.

Please observe good vaginal hygiene.
Use of condom is advisable, if needed.

For avoiding pregnancy related complications, please observe the suggested precautions.
You can use uterine relaxants , if needed, seek treating doctor's help.
Also, blood test of C reactive protein every 4 weeks will help to find id you are getting affected by infection, with regard to PROM .

I hope this answer helps you.
Thanks.
Dr. Purushottam Neurgaonkar
Above answer was peer-reviewed by : Dr. Nagamani Ng
doctor
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Follow up: Dr. Purushottam Neurgaonkar (2 hours later)
Thanks for your reply.
I have had a culture of the vaginal swab taken and it was found sensitive to co amoxiclav, which is what I am currently on.
1) why am I still experiencing quite severe itching despite being nearly half way through the course of antibiotics? Could it be a new infection or thrush? Or perhaps the antibiotic isn't working? Please let me know what is most likely.
2) why do I keep getting repeated vaginal infections. I am very careful with vaginal hygiene, and have not had sex since conception?
3) how dangerous is the klebsiella pneumoniae bacteria?
4) how common an infection is this in pregnancy?
5) how often should I have vaginal swabs to check for infection or would the blood tests be ok. I worry that repeat swabs could also cause infection.

I look forward to hearing.

Many thanks
doctor
Answered by Dr. Purushottam Neurgaonkar (2 hours later)
Brief Answer:
Add antifungals, antihistamines.

Detailed Answer:
Hi there,
Thanks for appreciating the answer and reverting back.

Let me answer your follow up queries.

1.Most of the times, itching associated with vaginal infection is commonly due to fungal element.
PLease seek prescription from your treating doctor for antifungal oral and vaginal tablets and antihistamines to relieve itching.

2.Although you are taking good precautions, due to altered scenario vagina is more prone for infection during pregnancy. Please do observe your hygienic practices regularly.

3. If treated completely and timely, this infection should not be worrisome during pregnancy.

4. Though this bacteria is not commonly seen to cause vaginal infection , it is not uncommon to get the Klebsiella infection.

5.I usually suggest to repeat the swab after 4 weeks. The swab it self is sterile. Taking swab from vagina should not cause infection.
Blood test for C reactive protein is advised 4 weekly. It is an indicator of products of inflammation formed as result of infection. It is not diagnostic test. Falling levels of CRP indicate that infection is getting treated.

I hope this answer helps you.
Thanks.
Dr. Purushottam Neurgaonkar
Above answer was peer-reviewed by : Dr. Kampana
doctor
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Follow up: Dr. Purushottam Neurgaonkar (7 hours later)
Thanks for your reply.
How can I know if the infection was treated in a 'timely fashion'? I was clear on 17th XXXXXXX and swabbed two weeks later so I must have had this infection for nearly three weeks. How dangerous is that?

I have an oral pro biotic called 'optibak' which contains over 2.3 billion live cultures specifically designed for women. Should i take this?

Many thanks
doctor
Answered by Dr. Purushottam Neurgaonkar (6 minutes later)
Brief Answer:
take oral probiotics. Monitor swabs and CRP

Detailed Answer:
Hi there,

I will suggest you to take your oral probiotic.
It is quite safe in pregnancy.

Secondly, you can get assured of complete treatment with negative swabs and negative C reactive protein levels.
If CRP levels are negative by now , you need not worry.

I hope this answer helps you.
Thanks.
Dr. Purushottam Neurgaonkar

Above answer was peer-reviewed by : Dr. Prasad
doctor
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Follow up: Dr. Purushottam Neurgaonkar (35 minutes later)
Thanks.
My local hospital claims I do not need a blood test as I have no fever.
They also said no need to re swab as the vaginal discharge is now normal colour (not yellow anymore).
I hope they are correct.
They have given me thrush treatment.
I will be seeing them next week for review. Do you think this will be ok?

Also, fetal heart rate was 160 today and only 124 last time measured. I read somewhere that by 18+ weeks heart rate should be slower and a fast rate could be indicative of the infection affecting the fetus. Two weeks ago the heart rate was 124. Should I be worried?
doctor
Answered by Dr. Purushottam Neurgaonkar (10 hours later)
Brief Answer:
follow your treating doctor. fetal heart rate normal.

Detailed Answer:
Hi there,
I will suggest you to follow the treatment as suggested by your treating doctor. It is ok if you are not having any symptoms and do not repeat the swab test.

Secondly, fetal heart rate usually taken as normal if it is in the range of 120 -160 beats per minute.
Anything below and above that needs to be a matter of concern.

So at present please do not worry.
If you have no symptoms, please follow the instructions as discussed earlier.
Enjoy your pregnancy.
Thanks
Dr. Purushottam Neurgaonkar
Above answer was peer-reviewed by : Dr. Nagamani Ng
doctor
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Follow up: Dr. Purushottam Neurgaonkar (19 hours later)
Thanks for your reply.

Can thrush occur in the rectal area or only in the vagina?
I am getting severe itching mainly in the rectal area (it is definitely not threadworm) and someone told me this could also be thrush. Is this true?
If so, how would I treat it?

Thanks
doctor
Answered by Dr. Purushottam Neurgaonkar (4 hours later)
Brief Answer:
Thrush can occur in anal area. oral and local antifungal.

Detailed Answer:
Hi there,
Thanks for appreciating the answer and reverting back.

Thrush, as it is commonly known us nothing but fungal infection.
It can occur around the opening of anus , may be due vaginal infection or simply separate anal infection.

In any case, you can use oral and local antifungal agents.
Please use Lactic acid containing vaginal wash on daily basis .

I hope this answer helps you.
Please DO rate this answer and write a review about the helpfulness of this answer. I will highly appreciate it.
Thanks.
Dr. Purushottam Neurgaonkar
Above answer was peer-reviewed by : Dr. Nagamani Ng
doctor
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Follow up: Dr. Purushottam Neurgaonkar (17 hours later)
Thank you for your reply.
I will rate your replies when all my questions have been answered.
I have been taking progesterone pesseries since having a bleed at 11 weeks. I am now 19 weeks pregnant and scared to stop the progesterone but I worry they might actually be contributing to my itchy vagina and rectum, and possibly even causing me thrush. I take one pesserie 400mg cyxlogest once daily, inserted through the rectum (not vaginally).
I was diagnosed with two subchorianic hematoma at 11 weeks, but they shrunk in size and there was only a trace of blood at a 15 week scan.
My questions:
1) could the progesterone be contributing to my problem?
2) is it safe to stop the progesterone now that I'm 19 weeks?

Thank you for your patience. I look forward to hearing.
doctor
Answered by Dr. Purushottam Neurgaonkar (6 hours later)
Brief Answer:
rectal use won't cause vaginal infection. stop progesterone for a while

Detailed Answer:
Hi there,
Thanks for appreciating the answers till now .

As per your history, if you are using progesterone tablets per rectally, then it is less likely that it is causing vaginal infection.

Usually, the placenta starts functioning at its full potential by 14 weeks of pregnancy.
Many times, progesterone support is advised till 14 weeks. It us basically pregnancy support hormone.
If you have no pain or bleeding now and your USG is nit showing any bleeding inside thenYou can opt to stop progesterone tablets for some time.
Usually USG for anomalies is advised at 18 to 20 weeks of pregnancy. If everything is fine in that reports, then you need not take progesterone tablets.

I hope this answer helps you.
Thanks.
Dr. Purushottam Neurgaonkar.
Note: Revert back with your gynae reports to get a clear medical analysis by our expert Gynecologic Oncologist. Click here.

Above answer was peer-reviewed by : Dr. Nagamani Ng
doctor
Answered by
Dr.
Dr. Purushottam Neurgaonkar

OBGYN

Practicing since :1992

Answered : 2236 Questions

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Suggest Treatment For Klebsiella Pneumoniae

Brief Answer: Pesonal hygiene. Antibiotics, antifungals, uterine relaxants,CRP Detailed Answer: Hi there. I have understood your concern. Firstofall do not panic. Please get culture ans sensitivity report of the vaginal swab done. I will suggest you to continue with your current antibiotic treatment for 7 days. Use of local antibacterial and antifungal vaginal pessaries for 7 days will be of help. Also, a suitable oral antifungal is advisable. I will suggest regular use of Lactic acid containingvaginal wash at bath time. Use of pre probiotics containing spore forms is advisable. I will suggest you to seek prescription help from your treating doctor for the same. Please observe good vaginal hygiene. Use of condom is advisable, if needed. For avoiding pregnancy related complications, please observe the suggested precautions. You can use uterine relaxants , if needed, seek treating doctor's help. Also, blood test of C reactive protein every 4 weeks will help to find id you are getting affected by infection, with regard to PROM . I hope this answer helps you. Thanks. Dr. Purushottam Neurgaonkar