HealthCareMagic is now Ask A Doctor - 24x7 | https://www.askadoctor24x7.com

question-icon

Suggest Treatment For Nausea After Taking Oncotrex

default
Posted on Tue, 7 Apr 2015
Question: I'm 40 years old lady. Suffering from some strange skin condition under feet and at the joint of thumbs. Shown to dermatologists. Doctor has prescribed Oncotrex 5mg once in a week. Initial 3 weeks I did not notice problem. Subsequently I had stomach problem and stopped that medicine. After recovery from stomach problem started the medicine again. This time I'm suffering from acute nausea and heavy head.

Skin condition is little better. How can I get rid of nausea immediately.
doctor
Answered by Dr. Dr. Kakkar (45 minutes later)
Brief Answer:
Adding a Folic acid supplement on non-methotrexate days would help

Detailed Answer:
Hello. Thank you for writing to us

I have understood you query.

The oral drug that you are taking is Methotrexate.

GI side effects like nausea are very common with Oral dosing of Methotrexate, though these side effects are usually not so bothersome on a low dose such as 5 mg/ week.

To counter this side effect it is routine to give Folic acid, on days when you are not taking Methotrexate (i.e the remaining 6 days).
This would normally prevent this complication from even developing.

Please note:- don't take folic acid on the day when you take Methotrexate.

To circumvent nausea another option is to administer Methotrexate via Injection rather than Oral route.

If nausea is really bothering you right now, your doctor or nurse can give you an additional pill to stop nausea e.g Ondansetron is quite effective for relieving nausea.

Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Dr. Kakkar (36 minutes later)
Thank you so much for your prompt reply!

Can you please confirm whether Folic Acid will not create constipation.

What is the reason for getting this psoriasis disease?

Regards..
doctor
Answered by Dr. Dr. Kakkar (4 minutes later)
Brief Answer:
Folic acid won't cause constipation

Detailed Answer:
Hi.

Folic acid does not cause constipation.
Psoriasis is an immune mediated disease wherein patients have scaly, red plaques on various body sites.
The underlying cause for psoriasis is a dysregulated immune system.
The disease is driven by inflammatory mediators (interleukins, cytokines etc) secreted by cells of the human immune system.

Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Dr. Kakkar (1 hour later)
Kindly let me know how to correct the dysregulated immune system?

Regards.
doctor
Answered by Dr. Dr. Kakkar (1 hour later)
Brief Answer:
Though it is possible to induce lasting remissions in psoriasis but no cure

Detailed Answer:
Hi.

There is no permanent cure for psoriasis.

Treatment is aimed at suppressing the abnormal immune response & regulating cytokine/ interleukins that drive psoriatic disease process.
Treatment measures includes oral immunosuppressives like methotrexate, oral cyclosporin.
Injectables biologic response modifiers like adalimumab (Humira) and ustekinumab etc are monoclonal human antibodies that specifically target/ block the interleukins/ cytokines that drive formation of psoriatic plaques.
Other systemic treatment options include phototherapy (PUVA, NB-UVB phototherapy).
Emollients, topical potent steroids, topical vitamin D analogues like calcitriol, calcipotriol etc are adjuvants to systemic treatment
While it is possible to control and induce lasting remissions in psoriasis but it is not yet possible to completely cure psoriasis.

Regards
Note: Hope the answers resolves your concerns, however for further guidance of skin related queries consult our Dermatologist.Click here to book a consultation

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Dr. Kakkar

Dermatologist

Practicing since :2002

Answered : 9612 Questions

premium_optimized

The User accepted the expert's answer

Share on

Get personalised answers from verified doctor in minutes across 80+ specialties

159 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
Suggest Treatment For Nausea After Taking Oncotrex

Brief Answer: Adding a Folic acid supplement on non-methotrexate days would help Detailed Answer: Hello. Thank you for writing to us I have understood you query. The oral drug that you are taking is Methotrexate. GI side effects like nausea are very common with Oral dosing of Methotrexate, though these side effects are usually not so bothersome on a low dose such as 5 mg/ week. To counter this side effect it is routine to give Folic acid, on days when you are not taking Methotrexate (i.e the remaining 6 days). This would normally prevent this complication from even developing. Please note:- don't take folic acid on the day when you take Methotrexate. To circumvent nausea another option is to administer Methotrexate via Injection rather than Oral route. If nausea is really bothering you right now, your doctor or nurse can give you an additional pill to stop nausea e.g Ondansetron is quite effective for relieving nausea. Regards