Suggest Treatment For Numbness And Muscle Weakness In My Arms And Legs Along With Back Pain

Posted on Wed, 27 Jun 2018

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Wed, 27 Jun 2018 Answered on

Wed, 2 Feb 2022 Last reviewed on

Question : I have taken testosterone injections from a testoterone therapy location for 3 months. I was retaining fluids and they started me on Anaprazole 2 weeks ago, half a tablet 48 hours after my injection. Since I've taken my last pill on Saturday I'm experiencing numbness/muscle weakness in my arms and legs. I have a some back pain and my eyes have been irritated/burning for short periods of time. I'm functioning but the symptoms aren't going away in the last 4 days. I called the location and they said the dosage I was on was too low for any major symptoms. All the symptoms I'm having are side effects of this drug. Any reason I should suspect it's something else and the timing is coincidental?

Answered by Dr. Mirjeta Guni (2 hours later)

Brief Answer:
About Anaprazole side effects:

Detailed Answer:

Hello,

Anaprazole is a new drug, used to treat gastric ulcers. It is still in clinical trials but the side effects are expected to be similar to the other proton pump inhibitor drugs (eg. Lansoprazole, Rabeprazole etc.).

I can not understand why was it recommended being taken 48 hours after testosterone injections.

Are you sure you are taking Anaprazole?
If yes, why was it prescribed? Could you please recheck and let me know further...

It'll be a pleasure to assist you further.

Kind regards,
Dr.Mirjeta

Above answer was peer-reviewed by : Dr. Arnab Banerjee

Follow up: Dr. Mirjeta Guni (18 minutes later)

Sorry I might have gotten the generic version wrong. Here is the formal name. Arimidex. It's half a pill once a week 48 hours after an injection..

Answered by Dr. Mirjeta Guni (11 hours later)

Brief Answer:
About anastrazole and it's side effects:

Detailed Answer:

Hi,

Now the situation is clear. Arimidex (anastrazole) is an antiestrogenic medication.

The problem with testosterone injections is that one of the main metabolites (estrogen), tends to get out of control, resulting in many of the same symptoms of low testosterone you had in the first place!

Fatigue, impotence, water retention (bloat), depression, and brain fog are all commonly associated with high estrogen.
The solution, is to add an estrogen lowering medication, commonly Arimidex (anastrozole) or Aromasin (exemestane), which essentially block the conversion of testosterone to estrogen.
It helps by forcing testosterone output to remain high while keeping estrogen levels low.

The symptoms you reported are side effects of Anastrazole but are considered minor side effects. If they persist and effect your quality of life you may stop the therapy.

Hope the information will help.
Best wishes,
Dr.Mirjeta

Above answer was peer-reviewed by : Dr. Vaishalee Punj