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Suggest Treatment For Prolonged Periods And Fluid Retention After Having Wysolone

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Posted on Mon, 30 Jun 2014
Question: mydaughter age 28 years was diagonise with sle 10years before .Treated with nephrologist and she took wysolone (PEDESOLONE ) of different dosage with covance (FOR HYPER) being main drugs with other drugs depending on condition of diseae .Dsdna became negative 6 years before ANA became negative 4 months before on blood test at present urine protine creatine ratio test shows out of nephrotic range with one/two plus of protine For long period she took 5 mg wysolone with 25to 50 mg covance At present 5TO 7,5 MG WYSOLONE DOES NOT WORK and ends up with fuid accumalation in body shows swelling of stomach and other complication which become ok with 10 mg wysolone BP normally 126/80 to 90 which increase on exertion This condition became after she took pause mf for excess mensuration as per gynacologist advice which is stopped on the advice of nephrologist In total her stamina and condition deterioted after taking pause mf KINDLY ADVISE
doctor
Answered by Dr. Venkat Sivayogi (19 hours later)
Brief Answer:
I HAVE SHORT LISTED THE POSSIBILITIES

Detailed Answer:
Hi,
Welcome to Healthcare Magic,

After going through the clinical history of your daughter it is evident that -

1. Mefenamic acid (NSAID drug) which present in the Pause-MF might have deteriorated the problem. Generally these pain killers which comes under category of NSAID drugs will have bad effects on the kidney. There by the normal filtration capacity of the kidney goes down and fluid accumalation starts.

2.As you have already stopped the drug advised by your nephrologist. no need to worry about it now.

3. Most of the time the kidney function returns to normal as soon as you stop the drug.

4. My suggestion is consult your nephrologist again re-check the status of her kidneys and follow his advice.


hope i have clarified your doubt , if you want to clarify few more you can contact me.

regards,
DR.VENKAT M.D

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Venkat Sivayogi (4 hours later)
as DSDNA & ANA has become negative whether lupus has disappeared
During mensuration she takesGYNAE.C.V.P WHETHER IT IS SAFE DRUG
SOME TIME HER PROTIEN AND POTASSIUM LEVEL GOES DOWN SHE TAKE ORAL POTASSIUM .WHAT IS GOOD FOOD FOR THIS
doctor
Answered by Dr. Venkat Sivayogi (7 hours later)
Brief Answer:
gynae cvp can be safely taken....

Detailed Answer:
welcome back,

Gyne CVP is vitamin tablet containing vit -c and iron . There is no problem in using this medicine.

Diet depends upon the severity of the kidney involvement and the present symptoms. For example kidney function is assessed through the blood urea, serum creatinine and ACR (albumin creatinine ratio).

Diet should be advised by a dietician who is under care of nephrologist after considering the above factors.


regards,
DR.VENKATM.D



Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Venkat Sivayogi (23 hours later)
her bp increase with little exertion of late since few days
she often get nail infection (puss which is removed by doctor & uses t bact creamt whether this has any thing with lupus
whether sle is reversable as ana is negative now
doctor
Answered by Dr. Venkat Sivayogi (39 minutes later)
Brief Answer:
SLE is a autoimmune disease which has ups&downs

Detailed Answer:
Welcome back,

Being a Auto -Immune disease SLE has remissions and exacerebations. So we cant clearly conclude that she is out of disease just with report of negative Anti-DsDNA .

Periodic checking of Anti-Ds DNA and ANA under care of Rheumatologist will make sense in order know the disease agressiveness.

coming the nail infections you are complaining ..is it involving single finger or multiple? ...If its the case of multiple finger involvement then we should consider the blood flow to the fingers is going well or not.

If ot involving one finger only then its possibly nail bed infection which can be treated by anti-biotics.


Hope I have clarified your query, you are welcome with any further doubts in case you have.
regards,
DR.VENKAT M.D
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
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Dr. Venkat Sivayogi

Internal Medicine Specialist

Practicing since :2007

Answered : 454 Questions

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Suggest Treatment For Prolonged Periods And Fluid Retention After Having Wysolone

Brief Answer: I HAVE SHORT LISTED THE POSSIBILITIES Detailed Answer: Hi, Welcome to Healthcare Magic, After going through the clinical history of your daughter it is evident that - 1. Mefenamic acid (NSAID drug) which present in the Pause-MF might have deteriorated the problem. Generally these pain killers which comes under category of NSAID drugs will have bad effects on the kidney. There by the normal filtration capacity of the kidney goes down and fluid accumalation starts. 2.As you have already stopped the drug advised by your nephrologist. no need to worry about it now. 3. Most of the time the kidney function returns to normal as soon as you stop the drug. 4. My suggestion is consult your nephrologist again re-check the status of her kidneys and follow his advice. hope i have clarified your doubt , if you want to clarify few more you can contact me. regards, DR.VENKAT M.D