Brief Answer:
quite a lot of features on this.

Detailed Answer:
oxymorphone is about twice as powerful as percocet/oxycodone/hydrocodone

there is not a strong reason to use both oxymorphone AND oxycodone. There is reason to use a long acting once a day drug (fentanyl) with shorter acting drugs for ups and downs of pain.

So, first the condition Some conditions can be fixed or helped to a significant degree and then the pain is lower.
Some conditions have particular features of the pain that can be directly addressed if not fixed. If nerve is the cause of the pain the nerve can be fixed or damped won or taken out, There can be other conditions that affect the pain the disease or the drug.

Actually first is the term "helping". I don't know what that means. Removing the condition? overcoming the despair about having an illness? Having no pain at all? Not having the expense and time and inconvenience from the illness? These are some of many things helping might mean that have one salient feature: drugs don't do that.

Then , there is the narcotics. People get used to them and they don't work as well. This is overcome by taking people off of them and putting them on a blocker for a week. If one started narcotics for the first time a week ago, forget I said that, it does not occur that fast. If one went lower on total narcotic strength, it will not do as much if one goes higher on narcotics they will do more. Long acting narcotics people get used to and they don't have as much of an effect faster than intermittently taking lower dose narcotics.

So, there are a number of areas in which the particular details of a particular patients pain will change everything. Frankly, not working with the narcotics and working with other features of the illness is generally a better choice.

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