Tminimal Right Precordial Repolarization Disturbance. Suggest

Posted on Thu, 16 May 2013

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Thu, 16 May 2013 Answered on

Tue, 11 Jun 2013 Last reviewed on

Question : my daughter is currently taking denzapine for her schizophrenia. She is only on250mg whichis not working. XXXXXXX has a problem with her QTC levels can trazodone add to this.

Answered by Dr. Jonas Sundarakumar (6 hours later)

Hello and welcome to Healthcare Magic. Thanks for your query.

Denzapine (Clozapine) is associated with QTc prolongation, however, a pathological or XXXXXXX prolongation is rare.

Trazadone is an anti-depressant which is also known to cause QTc prolongation. There are several reports of Trazadone causing QTc prolongation and rarely, a more serious resultant condition called "Torsades de pointes".

So, if a person already has a QTc problem, a lot of caution has to be taken while prescribing other drugs which can potentially worsen the problem.

Regards,
Dr. Jonas Sundarakumar
Consultant Psychiatrist

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar