Total Protein/creatinine Ratio Of 397mg/g. What Does This Signify?

Posted on Sun, 19 May 2013

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Sun, 19 May 2013 Answered on

Wed, 5 Jun 2013 Last reviewed on

Question : What does a total protein/creatinine ratio of 397mg/g signify? Also, what does a total protein, urine spot of 123mg/L mean?

Answered by Dr. Dr. Rakhi Tayal (32 minutes later)

Hello,
Thanks for posting your query.
Total protein/ creatinine ratio is used to monitor persistent proteinuria.
It is more accurate in identifying the renal function than 24 hour urine protein value.
A value of more than 300mg protein per gram of creatinine signifies a macroalbuminuria.
It can be due to a systemic disorder like hypertension, diabetes or a primary renal pathology. Further investigations are needed to identify the cause.
The total protein in urine in 24 hours should not exceed 80mg/day. A value of 123mg/ L is again increased and is suggestive of a renal pathology or a systemic disorder.
Hope this answers your query. I will be glad to answer the follow up queries that you have.
Please accept my answer in case you do not have further queries.
Wishing you good health.
Regards.
Dr. Rakhi Tayal.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar