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What Can Cause Misscarriage?

Posted on Tue, 1 Apr 2014

Question: Hi I have one misscarriage 14 months ago it was at 6 1/2 weeks , My misscarriage start with bleeding and clots in bleeding foe 2 weeks then in ultrasound they found no thing in the utrine all clear I did alot if tests all come negative , only MRHFR c677t hetro , and all others negative including factor V negative , Then we try again to get pregnant , we tried for one year i have mild endometriosis which treated with leaser by laproscopy and then take decapeptyl 11.25 mg which stop my period for 6 month My first period was on 12 feb and this last one finally i am pregnant Also my husband was poor morphology and motility he did varicocele repair and took supplements , finally his semen improved and i get pregnant My LMP 12 feb Beta on 10 mar was 54 Beta on 11 mar was 97 Beta on 13 mar was 193 I am really concernd about misscarriage again , My dr said the cause of misscarriage was mthfr c677 t hetro My homocystine is fine only 5 I am taking vaginal progesterone cyclogest 400 mg twice a day innohep 4500 iu daily sc injection Methylfolate 200 mcg pregnacare tab daily Please i am really thinking alot , am i going to lose this too ? What should i do ? Is my beta good ? Please help

Answered by Dr. Dr. Soumen Patra (49 minutes later)

Brief Answer: DO ONE TVS SCAN. BETA hCG IS NORMAL. Detailed Answer: Hello, Thanks for writing to us. Followings are my comments: 1) According to your last period date, you are now 4 weeks pregnant. At this stage, NORMAL Beta-hCG value is 5 – 426 mIU/ml. As per 13th March test result, your beta-hCG value is quite good. I suggest to undergo one Trans Vaginal ultrasound scan around 5 to 6 weeks to visualize the gestational sac and fetal heart beat. These are essential for healthy pregnancy. 2) MRHFR c677t hetero is one type of genetic mutation which leads to repeated miscarriage in some cases. I suggest to continue all the prescribed medicine and injection as per your doctor's advice. Do periodic check up, take healthy protein rich diet, avoid heavy work or long journey, drink plenty of water and take adequate bed rest. Hope, it helps for your information. Kindly, close the discussion if you don't have any other query. Wish your good health and successful motherhood. Regards, Dr Soumen For future query, you can directly approach me through http://doctor.healthcaremagic.com/Funnel?page=askDoctorDirectly&docId=63326

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Dr. Soumen Patra (42 minutes later)

thanks doctor , so you think my previous misscarriage was due to blood clots ?? do you think what i am doing now my medication is enough ?

Answered by Dr. Dr. Soumen Patra (7 minutes later)

Brief Answer: CHROMOSOMAL ABNORMALITY IS THE CAUSE. Detailed Answer: Hello, Thanks for follow up queries. 1) Most common cause of first trimester miscarriage is chromosomal abnormality (in your case MRHFR c677t mostly). Blood clots and infection are associated causes. 2) Current medications should be continued and these are quite enough at this stage of pregnancy. I suggest to undergo one TVS scan around 5 to 6 weeks. Hope, I have answered your queries. Kindly, close the discussion. All the best and good luck. Regards, Dr Soumen

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Dr. Soumen Patra (29 minutes later)

thanks dr , so CHROMOSOMAL ABNORMALITY , this cant be fixes or avoided ? and can be happen again right ?

Answered by Dr. Dr. Soumen Patra (15 minutes later)

Brief Answer: NO TREATMENT FOR ABNORMAL CHROMOSOMAL PATTERN. Detailed Answer: Hello, Thanks for query. There is practically NO treatment or preventive method for miscarriage, caused by abnormal chromosomal pattern or deformed fetus. It will be terminated naturally in most cases. However, it can't be predicted whether it will recur or happen again in successive pregnancy. Here, I suggest that you should undergo one TVS scan and proceed necessary investigation as your pregnancy progresses. Kindly, consult with OBSTETRICIAN. Goo luck. Kindly, close the discussion. Regards, Dr Soumen

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Dr. Soumen Patra (18 minutes later)

ok , i will go for scan next week , i am repeating my hcg every 2-3 days ,

Answered by Dr. Dr. Soumen Patra (2 minutes later)

Brief Answer: DO THE TESTS AS MENTIONED. Detailed Answer: Hello, Thanks for response. YES, you will continue the blood test for beta-hCG and undergo one TVS scan around 5 to 6 weeks to monitor fetal well being. Hope, it helps for you. All the best. Regards, Dr Soumen

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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar