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What Cause Sudden Abdominal Fat Gain While On Pradaxa?

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Posted on Tue, 11 Oct 2016
Question: Hi DR
I am on Pradaxa twice daily.( well tolerated)
Whilst on Warfarin I for 18 months ( through 2014- 2016) I gained significant abdominal fat.
I have had success with diet and exercise before. I have been a high performance athlete before now. I want to know whether it would be risky to re commence testosterone supplementation whilst on Pradaxa.
I have had multiple screening tests for low testosterone over a 10 year period with v similar results( low to v low natural testosterone) My brothers also have this issue.
doctor
Answered by Dr. Shehzad Topiwala (1 hour later)
Brief Answer:
Hormone Tests

Detailed Answer:
To my knowledge there is no major known direct conflict in using testosterone with pradaxa.
Testosterone can be a complex subject to interpret. Endocrinologists are best qualified to manage testosterone related matters, so it would be helpful if you were able to see one in person.

For example, the blood sample has to be drawn in the morning time before 10 am.

I typically run the following tests:

Total Testosterone
SHBG (Sex Hormone Binding Globulin)
FSH (Follicle Stimulating Hormone)
LH (Leutinizing Hormone)
Prolactin

But if a test called Free Testosterone is available in your laboratory and if they use Equilibrium Dialysis as the method, then there is not much of a need to check

Total Testosterone
SHBG

Once these results are in, one can get a fair idea whether or not Testosterone deficiency as the potential cause of your symptoms.
When I see someone like you in my practice, I typically order the following blood tests in addition to a detailed physical examination:

CBC (Complete Blood Count, also known as Hemogram; includes Hemoglobin, WBC and Platelet counts)
Electrolytes (Sodium and Potassium in particular)
HbA1c (Glycosylated Hemoglobin = your last 3 months' glucose average). Also known by other names such as GlycoHemoglobin or Glycated Hemoglobin or A1c
Liver function tests (SGOT , SGPT, Albumin, Bilirubin, Alkaline Phosphatase)
Kidney function tests (BUN, Creatinine)
TSH (checks your thyroid)
25 hydroxy Vitamin D levels (ideal range 40 to 60 ng/ml = 100 to 150 nmol/liter)

Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Shehzad Topiwala

Endocrinologist

Practicing since :2001

Answered : 1663 Questions

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What Cause Sudden Abdominal Fat Gain While On Pradaxa?

Brief Answer: Hormone Tests Detailed Answer: To my knowledge there is no major known direct conflict in using testosterone with pradaxa. Testosterone can be a complex subject to interpret. Endocrinologists are best qualified to manage testosterone related matters, so it would be helpful if you were able to see one in person. For example, the blood sample has to be drawn in the morning time before 10 am. I typically run the following tests: Total Testosterone SHBG (Sex Hormone Binding Globulin) FSH (Follicle Stimulating Hormone) LH (Leutinizing Hormone) Prolactin But if a test called Free Testosterone is available in your laboratory and if they use Equilibrium Dialysis as the method, then there is not much of a need to check Total Testosterone SHBG Once these results are in, one can get a fair idea whether or not Testosterone deficiency as the potential cause of your symptoms. When I see someone like you in my practice, I typically order the following blood tests in addition to a detailed physical examination: CBC (Complete Blood Count, also known as Hemogram; includes Hemoglobin, WBC and Platelet counts) Electrolytes (Sodium and Potassium in particular) HbA1c (Glycosylated Hemoglobin = your last 3 months' glucose average). Also known by other names such as GlycoHemoglobin or Glycated Hemoglobin or A1c Liver function tests (SGOT , SGPT, Albumin, Bilirubin, Alkaline Phosphatase) Kidney function tests (BUN, Creatinine) TSH (checks your thyroid) 25 hydroxy Vitamin D levels (ideal range 40 to 60 ng/ml = 100 to 150 nmol/liter)