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What Causes UTI When Diagnosed With Enlarged Prostrate?

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Posted on Mon, 5 Oct 2015
Question: Dear Sir,

My father has been diagnosed with enlarged prostrate and because of which he gets UTI. Considering his past medical history of Cardiomyopathy and COPD doctors are advising to avoid surgery for the time being ( a month or 2) as recently he had a compliant of type 2 respiratory failure and during that treatment only he developed UTI and later upon sonography enlarged prostrate was also discovered which resulted in growth of E Coli even after completing Meropenem antibiotics seven days course . It has also been diagnosed that due to prostrate the urininary bladder is unable to empty completely and due to which chances of recurrence of UTI always exist, though he never witnessed such synptoms in past i.e prior to recent type 2 respiratory failure.Now it has been advised that he should take Cranpac D along with Nitrophurantoin ( as per urine culture report) course for 3 weeks to prevent UTI. This is a stop gap arrangement till he is advised fit for prostrate surgery. Pls advise if this can be helpful. He is also taking Cap. Dutas and Cap Silodal 4 mg for prostrate and insulin for diabeties.
doctor
Answered by Dr. Matthew J. Mangat (50 minutes later)
Brief Answer:
Medical treatment is first line of action.

Detailed Answer:
Hello XXXXXXX and welcome to HCM.
As an Urologist, i can fully understand your concern.
With medical treatment, Silodosin 4mg and Dutasteride 0.5mg, majority people get good relief, from symptoms. Silodosin can be stepped up to 8mg later.
Medical treatment is always advised as first line of treatment.
Only if the response is not effective, need he consider surgery (TURP ).
With a cardiac and respiratory failure problem, his medical status is very much compromised. So surgery with medical condition, is definitely a high risk.
He will need a cardiac check-up,with echo scan and TMT, to assess risk.
Also, a respiratory failure suggests, severe COPD. He'll need to see a Pulmonologist, who will assess his respiratory status, with lung function tests.
You've to consider all these factors, before taking a decision on surgery.
So, it's best to wait and see the response to medical treatment.
The UTI will be treated with the present antibiotic, according to culture report.
Wishing him well.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Matthew J. Mangat (20 minutes later)
Dear Sir,

Thanks for your quick reply. I would also like to understand the effectiveness of Cranpac D for this treatment . Further my father has been prescribed Ceftum 500 for 5 days to be taken twice along with Nitrophorentoin for which he is taking Martifur 100 trice a day. Also I note from the culture report that one of the resistant drugs is Cefuroxime. Is there any concern in taking Ceftum and Martifur together.

Also if the symptom does not improves in next few days due to non emoltying of bladder completely, what is the alternative other than surgery for next 1-2 months.

Regards,

XXXX
doctor
Answered by Dr. Matthew J. Mangat (20 minutes later)
Brief Answer:
Avoid drugs seen as resistant in culture.

Detailed Answer:
Hi again.
Cranpac D is just given along with antibiotics as an adjunct.
It can't replace or act as antibiotic. It's an extract of cranberry juice with mannose-D.
If culture shows resistance to cefuroxime, then Ceftum(same), should be avoided.
Martifur 100mg twice daily, for 7 days is enough.
He should drink 8-10 glasses fluids daily.
He should wait for minimum 2 weeks, to see action of Silodosin with Dutasteride.
Then consider increasing Silodosin dose to 8mg., after checking with Urologist.
You may contact me, for an expert opinion.
Wish him well.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Matthew J. Mangat (9 minutes later)
Dear Sir,

Due to his cardiac problem water intake has been restricted to 1 litre perday and as per the recent USG the residual urine was around 220 ml, which is a huge amount.

The medicine Viz. Dutas is being taken once and Silodosin 4 mg is being taken twice a day. The medication has been started from 08th September 2015 only. My worry was to avoid infection due to high residual urine. As you have suggetsed we should see the effect of medication after 2 weeks, so till such time we have to keep our fingers crossed.

Regards,

XXXX

doctor
Answered by Dr. Matthew J. Mangat (20 minutes later)
Brief Answer:
Majority people respond very well to medical treatment.

Detailed Answer:
Hi again.
There're combinations of Silodosin and Dutasteride available.
Once a day dosing is sufficient, as it acts for 24 hours. XXXXXXX infection is taken care of by the antibiotic. What's there to worry about.
Ensure you're getting treated by a qualified Urologist.
Wishing your father well.
Note: For further follow up on related General & Family Physician Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Matthew J. Mangat

Urologist

Practicing since :1981

Answered : 1898 Questions

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What Causes UTI When Diagnosed With Enlarged Prostrate?

Brief Answer: Medical treatment is first line of action. Detailed Answer: Hello XXXXXXX and welcome to HCM. As an Urologist, i can fully understand your concern. With medical treatment, Silodosin 4mg and Dutasteride 0.5mg, majority people get good relief, from symptoms. Silodosin can be stepped up to 8mg later. Medical treatment is always advised as first line of treatment. Only if the response is not effective, need he consider surgery (TURP ). With a cardiac and respiratory failure problem, his medical status is very much compromised. So surgery with medical condition, is definitely a high risk. He will need a cardiac check-up,with echo scan and TMT, to assess risk. Also, a respiratory failure suggests, severe COPD. He'll need to see a Pulmonologist, who will assess his respiratory status, with lung function tests. You've to consider all these factors, before taking a decision on surgery. So, it's best to wait and see the response to medical treatment. The UTI will be treated with the present antibiotic, according to culture report. Wishing him well.