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What Causes Change In Brain Processing After Having Anti-psychotic Medications?

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Posted on Sat, 21 Jun 2014
Question: Hi Doctor,
I am 28 Yrs old male. I am suffering from schizophrenia and taking anti-psychotic medication for the past 2 Yrs. I feel that my aptitude and problem solving skills has gone down after the medication. During disease I was able to do the work with high accuracy and I got the IQ of 125 in the company test, but now after the medication I am fine and don’t have hallucinations, but I take longer time to do the same task and I got IQ score of 60. Right now I am taking 1mg Risdone at night and doctor says it happens in this disease. Please suggest if there any way I can have my intelligence back.
doctor
Answered by Dr. Manisha Gopal (35 minutes later)
Brief Answer:
life style changes and puzzles

Detailed Answer:
Hello,
Your doctor is right in a way that the illness causes some change in brain processing which may cause a feeling of dullness in the patient..espically, in youngsters who are able to diffrentiate it..
But the point that you can feel the difference : also reflects that if you work on it - there is a significant chance of improvement.

I always ask my patients who are on antipsyhotics to do these things:

1. running or brisk walking daily for 1/2 hr.
2. to start nuts like almonds or walnuts (naturally good for brain functioning)
3. add a good multivitamin to your daily diet to fulfill some minor nutrient deficincies which may be involved in slowness
4. to become more social - socialization is a cure of many things in itself..and most of patients, post schizophrenia episode tend to remain aloof..avoid friends ..dont do that..it is counter productive for intellegence
5. start solving more puzzles and matematical or apptitude problems...you will improve..

But always keep in mind that medicine should not be stopped without doctors advice. The illness can recur, so take meds till he asks you to stop.

P.S.- never take tobacco/ alcohol or any abusive substance. This will cause a permanent damage in neurons. When you keep away from these things- there is definite improvement.

Wish you good luck
Dr. Manisha Gopal
MD Psychiatry
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Manisha Gopal (18 minutes later)
I studies that schizophrenia is caused because of excess dopamine. This neurotransmitter is responsible for pleasure and intelligence. Is this possible because of medication my dopamine level in brain has gone below normal and that is why I am not able to think well. Is there any medical test to check my dopamine level, so that if it’s found low than I can ask my doctor to stop the medication?
As you were saying tobacco is harmful, I also ask the doctor about my smoking. I use to smoke 10 cigarettes a day and doctor says that you have to make it stop. But he agrees that this has nothing to do with schizophrenia. So how serious is my smoking, one thing I want to say smoking helps me in my work and give me good concentration.
doctor
Answered by Dr. Manisha Gopal (8 hours later)
Brief Answer:
smoking is definitely harmful in this illness

Detailed Answer:
Hello,
First thing is - schizophrenia has many things to do with smoking..so many people diagnosed with this illness smoke; as they feel it enhance their skills and conentration which otherwise seem to be compromised for soemtime after illness.
Somking tobacco activates nicotinic 7-alpha receptors which enhace skills for sometime..but eventually, the smoking becomes more and more and at the same time compromise drug level and may even lead to relapse of illness. Smoking cigaretee is such a big addiction in patiens with chronic schizophrenia that in old times it was used as a token to make them do something impprtant for them or to make them take medicines regularly..

So, dont indulge in momentary improvement in concentration and smoke -beacuse it is definitetly harmful in all possible ways.

Now, dopamine levels- its not just altered dopamine but several other chemicals which are disturbed in this illness. Resperidine and other antipsychotics work on several mechanisms and make the person stable. The neruochemical imbalance in psyhiatric illnesses is such a complicated phenomenon that several theories are still unexplained by science..
these chemicals can be tested in research labs, may be abroad, but I dont think this is done in XXXXXXX

So, just by testing dopamine wont clarify anything. Its better that you discuss the dosage adjustment or may be shifting you to a better and mild molecule with your doctor.

Doing anything in hurry might cause a relapse which will eventually mean taking drug for almost all life..which neither you nor any psychiatrist would like to happen. We ( doctors) know these illness more than anyone you have in near visinity and we always want the best for our patients. Its not that we dont want to stop the meds...but we know the risks involved and what the repurcussions can be...so, just for the patients ( who are usually young when they get this illness) we care for and fear makng hurry..Ok..So, dont smoke..talk about reduction of drugs initially but dont force..

Please follow lifestyle changes as I mentioned..atleast try them..they are good and effective.

Hope that the reply is useful for you.

Please ask more queries to clarify doubts.
Dr. Manisha Gopal
MD Psychiatry
Note: For further guidance on mental health, Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Manisha Gopal

Psychiatrist

Practicing since :2005

Answered : 947 Questions

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What Causes Change In Brain Processing After Having Anti-psychotic Medications?

Brief Answer: life style changes and puzzles Detailed Answer: Hello, Your doctor is right in a way that the illness causes some change in brain processing which may cause a feeling of dullness in the patient..espically, in youngsters who are able to diffrentiate it.. But the point that you can feel the difference : also reflects that if you work on it - there is a significant chance of improvement. I always ask my patients who are on antipsyhotics to do these things: 1. running or brisk walking daily for 1/2 hr. 2. to start nuts like almonds or walnuts (naturally good for brain functioning) 3. add a good multivitamin to your daily diet to fulfill some minor nutrient deficincies which may be involved in slowness 4. to become more social - socialization is a cure of many things in itself..and most of patients, post schizophrenia episode tend to remain aloof..avoid friends ..dont do that..it is counter productive for intellegence 5. start solving more puzzles and matematical or apptitude problems...you will improve.. But always keep in mind that medicine should not be stopped without doctors advice. The illness can recur, so take meds till he asks you to stop. P.S.- never take tobacco/ alcohol or any abusive substance. This will cause a permanent damage in neurons. When you keep away from these things- there is definite improvement. Wish you good luck Dr. Manisha Gopal MD Psychiatry