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What Causes Change In Facial Appearance When Suffering From Cushings Disease?

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Posted on Fri, 30 Jan 2015
Twitter Fri, 30 Jan 2015 Answered on
Twitter Sat, 28 Feb 2015 Last reviewed on
Question : Hello Doctor
I had surgery about 8 weeks ago for cushings disease. Had a tumor removed from my pituitary gland. My problem is the appearance of my face seems to change. My facial cheeks would look big on some days and normal on others. Sometimes i can actually feel the weight of my facial cheeks. Do you know what can cause this? I also have the results from lab work done a couple weeks ago

doctor
Answered by Dr. Shehzad Topiwala (4 hours later)
Brief Answer:
Cushings

Detailed Answer:
I have reviewed the attached laboratory results.

They look fine. The testosterone result however is pending.

The face along with the entire body undergoes many changes in contour, in a person affected by Cushings disease.
After surgery, many of thee improve and tend to get back towards normal.

This of course is dependent on the degree of remission (cure) achieved.

I see your cortisol is in the range of 17 which appears normal.

I suggest checking with your endocrinologist to see if any 'dynamic' tests like Overnight Dexamethasone suppression tests, or midnight salivary cortisol test need to be performed to assess current status of cortisol in your body.
The reason is that, in order to assess whether or not the surgery has achieved good results, one needs to perform one or more of the types of tests I have mentioned above, and not morning cortisol alone. (I have noted that you had this lab drawn at 8.30 am )


Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Shehzad Topiwala (42 hours later)
Thank you for the reply.

I have also been having trouble digesting food. Once i eat a meal i notice my stomach distending in other words appearing larger. I thought it would of improved after i had surgery but unfortunattely it has not. Do you think i should see a gastrologist?
doctor
Answered by Dr. Shehzad Topiwala (10 hours later)
Brief Answer:
Follow up

Detailed Answer:
Yes it would be worthwhile consulting a gastroenterologist
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Shehzad Topiwala

Endocrinologist

Practicing since :2001

Answered : 1663 Questions

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What Causes Change In Facial Appearance When Suffering From Cushings Disease?

Brief Answer: Cushings Detailed Answer: I have reviewed the attached laboratory results. They look fine. The testosterone result however is pending. The face along with the entire body undergoes many changes in contour, in a person affected by Cushings disease. After surgery, many of thee improve and tend to get back towards normal. This of course is dependent on the degree of remission (cure) achieved. I see your cortisol is in the range of 17 which appears normal. I suggest checking with your endocrinologist to see if any 'dynamic' tests like Overnight Dexamethasone suppression tests, or midnight salivary cortisol test need to be performed to assess current status of cortisol in your body. The reason is that, in order to assess whether or not the surgery has achieved good results, one needs to perform one or more of the types of tests I have mentioned above, and not morning cortisol alone. (I have noted that you had this lab drawn at 8.30 am )