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What Causes Colorectal Cancer?
Question: I have been diagnosed Colorectal cancer Spread to Liver -Multiple hypoechogenic foci measuring 8 to 10 MM (3 nos) and largest 16x22mm presacral region .No paraqoetie LNS. Liver limited disease. Doctors advised to go thru 4 cycles of Avastin+FOLFIRI (Avastin 400mg+IRINOTECAN 270mg+Levocovorin 300 Mg +5FU 3600mg) per cycle . Do PET CT after 4 cycles and assess the progress for next cycle of treatment.
I would like to have your views on line of treatment and suggest few tips in managing these cycles and improve recovery part. Would like to to success rate on this line of treatment. I am 58 years old . First Cemo cycle not much side effect except constipation. Thank you for your time .
I would like to have your views on line of treatment and suggest few tips in managing these cycles and improve recovery part. Would like to to success rate on this line of treatment. I am 58 years old . First Cemo cycle not much side effect except constipation. Thank you for your time .
Brief Answer:
it is treatable condition
Detailed Answer:
Hi
Thanks for your query.
Yes, this is indeed liver metastatic disease. Howver, there are options. As your doc has outlined, FOLFIRI + avastin is a good combo to start with. After few cycles, another PET-CT to assess response and decide on surgery. Maybe the liver lesions will be operable after few cycles. But this depends on lot of factors, the size and number (as seen on images), location of the mets, etc. As both lobes are involved, it is a bit borderline scenario but not impossible.
We also need to get Kras mutation tested, as then we can have another targeted option in hand (cetuximab/panitumumab).
Regarding managing the cycles, you need to take home-cooked diet, fruits and vegetables to be washed well. Maintain enough calories and protein in diet. Maintain oral hygiene with appropriate mouth washes as advised. Not to strain during stools and take laxatives to soften the stools. Rest take everything as it comes, eg diarrhea, fever, etc. Your doc will give necesary emergency medicines in case required.
You seem to be tolerating well, hence not to worry too much.
Hope I have answered your query. I will be available to answer further followup queries, if any.
it is treatable condition
Detailed Answer:
Hi
Thanks for your query.
Yes, this is indeed liver metastatic disease. Howver, there are options. As your doc has outlined, FOLFIRI + avastin is a good combo to start with. After few cycles, another PET-CT to assess response and decide on surgery. Maybe the liver lesions will be operable after few cycles. But this depends on lot of factors, the size and number (as seen on images), location of the mets, etc. As both lobes are involved, it is a bit borderline scenario but not impossible.
We also need to get Kras mutation tested, as then we can have another targeted option in hand (cetuximab/panitumumab).
Regarding managing the cycles, you need to take home-cooked diet, fruits and vegetables to be washed well. Maintain enough calories and protein in diet. Maintain oral hygiene with appropriate mouth washes as advised. Not to strain during stools and take laxatives to soften the stools. Rest take everything as it comes, eg diarrhea, fever, etc. Your doc will give necesary emergency medicines in case required.
You seem to be tolerating well, hence not to worry too much.
Hope I have answered your query. I will be available to answer further followup queries, if any.
Note: For further queries related to kidney problems Click here.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Answered by
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