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What Causes Dizziness, Fatigue, Chest Pain And Tingling Feet?

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Posted on Mon, 16 Mar 2015
Question: Hi,
I had an MRI with results showing diminished signal for vertebral bone marrow and it said could be from renal disease, anemia or infiltrative processes. Under impressions it says abnormal bone marrow, infiltrative processes cannot be excluded. I am 35, white female, non smoker, relative good health, Vitamin D deficient with low sugar and hypothyroidism. My symptoms are dizziness, fatigue, chest pain, nausea, tingling feet. My dr. mentioned multiple meyloma out of nowhere and has me seeing an oncologist. They have ruled out MS, lupus, infections, etc. clear brain mri, clear chest ct scan, I don't know where this suggestion is coming from.
doctor
Answered by Dr. Vivek Chail (24 minutes later)
Brief Answer:
The suspicion of myeloma is from bone marrow appearance on MRI scan

Detailed Answer:
Hi XXXXXX,
Thanks for writing in to us.

I have read through your query in detail.
The bone marrow in a young adult contains more of red bone marrow and slowly with increasing age, this red bone marrow is replaced with yellow bone marrow. The presence of red marrow indicates more red blood cell formations and this decreases with time as we grow old.

The marrow usually is expected to be slightly lighter when normal. In conditions where the marrow is very dark, an underlying process concerning the bone marrow is to be considered. Since you have dizziness, chest pain, fatigue, nausea and tingling feet, these might be related to a condition in the marrow that is not producing normal blood cells.

The dark marrow can also be seen in kidney disease. Myeloma is one of the disorders affecting bone marrow appearances and it needs to be considered and probably you might require a bone marrow aspiration for evaluation, which is a confirmation test.

Hope this answers your question. Please feel free to correct any oversight in my interpretation of your problems and discuss them in detail as per your requirements.

Hope your query is answered.
Do write back if you have any doubts.

Regards,
Dr.Vivek
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Vivek Chail (3 minutes later)
I also have Hepatitis C and don't know if that would affect it. Is myloma the only thing that it could be or are there other potential causes.
doctor
Answered by Dr. Vivek Chail (9 minutes later)
Brief Answer:
HCV infection and treatment might have a role and myeloma isnt the only one

Detailed Answer:
Hi XXXXXX ,
Thanks for writing back with an update.

Medical literature shows that patients with hepatitis C virus (HCV) infection develop a number of hematologic disorders, with benign and malignant B-cell proliferations being the most common. Hematologic disorders mean conditions involving bone marrow. It has also been found that HCV infected patients are also prone to developing peripheral cytopenias, the etiologies of which are multifactorial and include hypersplenism and/or antiviral medications.

Myeloma is not the only condition to be investigated but because it is among the commonest therefore usually the first one to be considered. There are many conditions together grouped as myeloproliferative disorders and the distinction is made on basis of bone marrow biopsy.

Regarding your HCV infection, I suggest you please discuss the role of the virus and medications given to you with your doctor. The pathologist must also be made aware of your HCV infection when reading your biopsy material.

Hope your query is answered.
Do write back if you have any doubts.

Regards,
Dr.Vivek
Note: For further queries related to kidney problems Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Vivek Chail

Radiologist

Practicing since :2002

Answered : 6874 Questions

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What Causes Dizziness, Fatigue, Chest Pain And Tingling Feet?

Brief Answer: The suspicion of myeloma is from bone marrow appearance on MRI scan Detailed Answer: Hi XXXXXX, Thanks for writing in to us. I have read through your query in detail. The bone marrow in a young adult contains more of red bone marrow and slowly with increasing age, this red bone marrow is replaced with yellow bone marrow. The presence of red marrow indicates more red blood cell formations and this decreases with time as we grow old. The marrow usually is expected to be slightly lighter when normal. In conditions where the marrow is very dark, an underlying process concerning the bone marrow is to be considered. Since you have dizziness, chest pain, fatigue, nausea and tingling feet, these might be related to a condition in the marrow that is not producing normal blood cells. The dark marrow can also be seen in kidney disease. Myeloma is one of the disorders affecting bone marrow appearances and it needs to be considered and probably you might require a bone marrow aspiration for evaluation, which is a confirmation test. Hope this answers your question. Please feel free to correct any oversight in my interpretation of your problems and discuss them in detail as per your requirements. Hope your query is answered. Do write back if you have any doubts. Regards, Dr.Vivek