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What Causes Elevated Bilirubin Count In Blood While On Vyvanse And Trazadone?

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Posted on Tue, 19 Jan 2016
Question: My billirubin level is 1.5. Just got over the flu before blood work.I take vyvanse, lexapro, trazadone, klonopin as needed. Liver emzynes normal. Opinion?
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Answered by Dr. Panagiotis Zografakis (36 minutes later)
Brief Answer:
probably Gilbert's syndrome

Detailed Answer:
Hello,

isolated low bilirubin elevation is usually caused by the Gilbert's syndrome which is a completely harmless condition. In Gilbert's syndrome the liver cannot process bilirubin properly which results in indirect bilirubin elevation. Bilirubin may get higher during fasting or when the patient is ill. Another measurement a few days later is recommended to check whether bilirubin is rising more than expected or not. In Gilbert's syndrome it's usually around 2mg/dL but it may rise up to 5mg/dL. Anything above the aforementioned levels should warrant investigation for its cause.

So in conclusion, it sounds like Gilbert's syndrome. Since you don't have symptoms or other biochemical findings, the best course of action would be a repeat measurement of liver function tests a few days later.

Kind Regards!
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Panagiotis Zografakis

Internal Medicine Specialist

Practicing since :1999

Answered : 3810 Questions

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What Causes Elevated Bilirubin Count In Blood While On Vyvanse And Trazadone?

Brief Answer: probably Gilbert's syndrome Detailed Answer: Hello, isolated low bilirubin elevation is usually caused by the Gilbert's syndrome which is a completely harmless condition. In Gilbert's syndrome the liver cannot process bilirubin properly which results in indirect bilirubin elevation. Bilirubin may get higher during fasting or when the patient is ill. Another measurement a few days later is recommended to check whether bilirubin is rising more than expected or not. In Gilbert's syndrome it's usually around 2mg/dL but it may rise up to 5mg/dL. Anything above the aforementioned levels should warrant investigation for its cause. So in conclusion, it sounds like Gilbert's syndrome. Since you don't have symptoms or other biochemical findings, the best course of action would be a repeat measurement of liver function tests a few days later. Kind Regards!