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What Causes Exhaustion While On Rifampicin And Cefuroxime?

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Posted on Tue, 6 Dec 2016
Question: Hi, I am on Rifampicin, Lymecycline and cefuroxime for the last 3 months. Almost a wk into 4ty. I am still very exhausted and only get about 2 days in 10 where I feel good. It doesn't seem to kast. Can I do anything to helo myself? I do take immune support herbs and supplements. XXXXXXX
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Answered by Dr. Tushar Kanti Biswas (8 hours later)
Brief Answer:
Chronic Lyme disease

Detailed Answer:
Hi,

Thank you for your query. I can understand your concerns.

It seems you are having Chronic Lyme disease(onset 2009). You must have received a course of antibiotic therapy initially. Presently you are again on a combination of Rifampicin,Lymecycline and cefuroxime axetil for 3 months (12 weeks). Usually this combination of antibitics is needed for only 30-60 days.
Approximately 15% of patients experience a Jarisch-Herxheimer-like (herx as mentioned by you) reaction during the first 24 h of therapy.Although an occasional patient requires a second course of antibiotics, there is no indication for multiple, repeated antibiotic courses in the treatment of Lyme disease.

This chronic Lyme disease or post–Lyme syndrome is sometimes a disabling condition that is similar to chronic fatigue syndrome or fibromyalgia.Such
patients are best treated for the relief of symptoms rather than with
prolonged courses of antibiotics (as you are on presently).

You can try Yoga or tai-chi exercise therapy.














Regards

Dr. T.K. Biswas M.D. XXXXXXX
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Nagamani Ng
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Answered by
Dr.
Dr. Tushar Kanti Biswas

Internal Medicine Specialist

Practicing since :1975

Answered : 1920 Questions

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What Causes Exhaustion While On Rifampicin And Cefuroxime?

Brief Answer: Chronic Lyme disease Detailed Answer: Hi, Thank you for your query. I can understand your concerns. It seems you are having Chronic Lyme disease(onset 2009). You must have received a course of antibiotic therapy initially. Presently you are again on a combination of Rifampicin,Lymecycline and cefuroxime axetil for 3 months (12 weeks). Usually this combination of antibitics is needed for only 30-60 days. Approximately 15% of patients experience a Jarisch-Herxheimer-like (herx as mentioned by you) reaction during the first 24 h of therapy.Although an occasional patient requires a second course of antibiotics, there is no indication for multiple, repeated antibiotic courses in the treatment of Lyme disease. This chronic Lyme disease or post–Lyme syndrome is sometimes a disabling condition that is similar to chronic fatigue syndrome or fibromyalgia.Such patients are best treated for the relief of symptoms rather than with prolonged courses of antibiotics (as you are on presently). You can try Yoga or tai-chi exercise therapy. Regards Dr. T.K. Biswas M.D. XXXXXXX