What Causes Fluctuation In BP While On Metformin And Glipizide?

Posted on Sun, 17 Apr 2016

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Sun, 17 Apr 2016 Answered on

Thu, 9 Jun 2016 Last reviewed on

Question : I have diabetes type 2 and I am taking metformin 1000mg together with glipizide, since yesterday my sugar level has been fluctuating above 300 to 160, I am female 60 years old.

Answered by Dr. Shehzad Topiwala (34 minutes later)

Brief Answer:
Diabetes

Detailed Answer:
It is not the objective of this forum to provide specific medications and doses.

You will be best served by consulting an Endocrinologist in person.

When I see someone like you in my practice, I typically order the following blood tests in addition to a detailed physical examination:

CBC (Complete Blood Count, also known as Hemogram; includes Hemoglobin, WBC and Platelet counts)
Electrolytes (Sodium and Potassium in particular)
HbA1c (Glycosylated Hemoglobin = your 3 month glucose average)
Liver function tests (SGOT , SGPT, Albumin, Bilirubin, Alkaline Phosphatase)
Kidney function tests (BUN, Creatinine)
TSH
12 hour Fasting Lipid profile
Urine albumin to Creatinine Ratio
25 hydroxy Vitamin D

After reviewing results, I consider dose increases of the current medications versus adding others such as Januvia.

Then I advise the patient to come back in a few days with home log of blood glucoses, for further dose adjustments if necessary

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar