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What Causes Generalized Anxiety Disorder?

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Posted on Tue, 29 Apr 2014
Question: I am a female, 57 years old with anxiety tendency since childhood. I had a few crisis in my life often triggered by an outside events, but I always became better again after a few months. I had 2 jobs as accounts manager, one for 18 years and the current one for 13years. In 2010, for a crisis of high anxiety after a bad flu, I was given Xanax XR 1mg that I took for about 6 months, than I tapered down to Xanax XR 0.5mg that I took for about 9 months, than I switched to Xanax 0.25 mg 2x/day for another few months, than I cut down to 0.25mg/day for a while, I am not sure how long, than to 1/2 of 0.25mg/day and than to 1/4 of 0.25mg/day that I took for a couple of years, I think. Then at the end of last July 2013, I stopped it. First I did not notice anything, but later I developed insomnia and in October I started a full blown severe anxiety episode with debilitating anxiety basically all day long, which has not stopped as of today. In December I went to my doctor who gave me Ativan 1mg 2x/day that I took for over 3 months. I than started to feel worse and worse and now I am trying to taper out of the Ativan and having a horrible time. I am very scared and not quite sure what is happening to me. If I know that it is withdrawal, then I will try to tough it through, hoping that I will eventually get better. But my fear is that it is the underlying anxiety which is coming back or getting worse and this totally discouraged me . I am very worried because the onset of this severe anxiety episode which started last October has no real reason that I am aware of. My question to you is : Could it be delayed withdrawal from the long term Xanax I took even though it was such a small dose ? After stopping it in July, I took occasionally some Ambien because I could not sleep. But I took it no more than 1 or 2x/week.
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Answered by Dr. Abhishek Kapoor (20 minutes later)
Brief Answer: Better to use sedative antidepressant Detailed Answer: Hi Thanks for using healthcare magic. I, Dr Abhishek Kapoor, would help you in this query. I think, you have generalized anxiety disorder and that may be due to underline anxious personality traits. Initially you were better with xanas due to its anxiolytic effect, but due to underline anxiety disorder, you again got same kind of symptoms. This is not withdrawal symptoms, but typical relapse of anxiety disorder. Now you are taking ativan which consists of lorazepam and in that case, you should try sedative mirtazapine or trazodone. It would help to control anxiety as well as help you to decrease the dose of ativan. For sleep, you can try ambien(zolpidem) on sos basis due to its less abuse and dependence potential. In case, you need further help, you can ask. Regards Dr. Abhishek Kapoor Psychiatrist
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Dr. Abhishek Kapoor

Psychiatrist

Practicing since :2007

Answered : 2496 Questions

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What Causes Generalized Anxiety Disorder?

Brief Answer: Better to use sedative antidepressant Detailed Answer: Hi Thanks for using healthcare magic. I, Dr Abhishek Kapoor, would help you in this query. I think, you have generalized anxiety disorder and that may be due to underline anxious personality traits. Initially you were better with xanas due to its anxiolytic effect, but due to underline anxiety disorder, you again got same kind of symptoms. This is not withdrawal symptoms, but typical relapse of anxiety disorder. Now you are taking ativan which consists of lorazepam and in that case, you should try sedative mirtazapine or trazodone. It would help to control anxiety as well as help you to decrease the dose of ativan. For sleep, you can try ambien(zolpidem) on sos basis due to its less abuse and dependence potential. In case, you need further help, you can ask. Regards Dr. Abhishek Kapoor Psychiatrist