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What Causes Increased SGPT Level?

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Posted on Wed, 7 May 2014
Question: Yes I am seriously disturbed I just got my labs back. My liver tests are off the charts! What does this mean? Am I Going to die? female...53 years old. Social drinker 2 drinks a day maybe......maybe not. ...just lost 40 lbs on a low carb diet. Over the course of a year. I take topiramate 100 mg and phentermine 37.5 mg for appetite suppressants. The last couple of weeks have been on oxycodone/acetaminophen 325mg once a day at bedtime and maybe 800mg ibuprofen during the day for pain. I have severe degenerative arthritis in both of my feet....big toe joints and ankles...and my right shoulder has been causing me to lose sleep. Severe pain I cry every day. Arthritis I don't know, I will be asking my doc on the 24th of this month. But I just saw my labs and am very scared. VERY! I don't feel my liver failing!!!!!!! My heart feels fine! Oh and yea! CK TOTAL 174 29-143 U/L H My CK total! What the hell? My heart feels fine!!!!!! What is wrong with me? I seriously want to cry right now and want to see my doctor immediately and I know that is not possible..... AST (SGOT) 150 10-35 U/L H ALT (SGPT) 247 6-29 U/L H ALKALINE PHOSPHATASE 161 33-130 U/L H
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Answered by Dr. Indu Kumar (43 minutes later)
Brief Answer: You need proper clinical exam & investigations. Detailed Answer: Hello XXXX Thanks for writing to HCM You need proper clinical examination and further investigations. You also need few other investigations like routine hemogram,Random blood sugar(RBS),Complete Liver function test(LFT),Renal function test(RFT),Lipid profile,Viral markers,ECG in all leads,Ultrasound of abdomen,Urine RE/ME.Further investigations can be done if needed. Increased SGPT indicates liver injury and it may be due to alcohol,hepatitis etc.It is important to know bilirubin and GGT level. Due to increased CK,heart status should also be confirmed.ECHO should be done to assess functional status of the heart. CK is increased in many other conditions besides heart problem,so it should be clinically correlated. Proper treatment depend upon clinical findings and investigation reports. You may need medicines for increased SGPT. You should avoid alcohol completely.This is very necessary for your healthy liver. You should also avoid fatty food. Get well soon. Hope I have answered your question. Further queries are most welcome. Take Care Dr.Indu XXXXXXX
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Indu Kumar

Radiologist

Practicing since :2004

Answered : 6729 Questions

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What Causes Increased SGPT Level?

Brief Answer: You need proper clinical exam & investigations. Detailed Answer: Hello XXXX Thanks for writing to HCM You need proper clinical examination and further investigations. You also need few other investigations like routine hemogram,Random blood sugar(RBS),Complete Liver function test(LFT),Renal function test(RFT),Lipid profile,Viral markers,ECG in all leads,Ultrasound of abdomen,Urine RE/ME.Further investigations can be done if needed. Increased SGPT indicates liver injury and it may be due to alcohol,hepatitis etc.It is important to know bilirubin and GGT level. Due to increased CK,heart status should also be confirmed.ECHO should be done to assess functional status of the heart. CK is increased in many other conditions besides heart problem,so it should be clinically correlated. Proper treatment depend upon clinical findings and investigation reports. You may need medicines for increased SGPT. You should avoid alcohol completely.This is very necessary for your healthy liver. You should also avoid fatty food. Get well soon. Hope I have answered your question. Further queries are most welcome. Take Care Dr.Indu XXXXXXX