What Causes Low BP While On Zoryl-M2 And Galvus In A Diabetic Patient?

Posted on Fri, 15 Jul 2016

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Fri, 15 Jul 2016 Answered on

Mon, 1 Aug 2016 Last reviewed on

Question : My Father aged 77 years is Diabetic since for the past 20 years.He also had CABG done 10 years back. Now he is on Zoryl M2 and Galvus Met(50/500).He takes Zoryl M2 once in the morning before breakfast and then Galvus Met after breakfast.And in the night,he takes Zoryl M2 after dinner.With this,what I am observing is that his blood sugar goes low during evening (around 7 to 8 PM) ,and couple of reading showed the blood sugar as low as 30 to 40 .I have my own doubt with the medicines.I feel since both has metamorfin ,it is too much for my father.Any suggestion?

Answered by Dr. Dr. Phanindra Dulipala (31 minutes later)

Brief Answer:
Replace afternoon tablet(Galvus met 50/500) with plain metformin 500.

Detailed Answer:
Hi Sir, gone through your query and understood your concerns.

Sir if the problem is only with the sugar levels in the evening, advice him to take only Metformin 500 in place of Galvus met 50/500. As you asked metformin is alright, its not too much.

If the Fasting and Post Prandial sugar levels are also low(which is not mentioned in the query), then you need to stop afternoon medicine first. But if they are in the normal range, then only change needed is as mentioned above and advice to take some sugarless snacks in the evening at around 4-5 o clock.

Hope this helps you,
Thank you

Above answer was peer-reviewed by : Dr. Nagamani Ng

Follow up: Dr. Dr. Phanindra Dulipala (41 minutes later)

Thanks for the reply Dr.
My Father takes Zoryl M2 once in the morning before breakfast and then Galvus Met immediately after breakfast.There is no medicine in the afternoon. And in the night, he takes Zoryl M2 after dinner.

And the random sugar level is around 160.

Answered by Dr. Dr. Phanindra Dulipala (10 minutes later)

Brief Answer:
Stop Galvus met50/500 for two weeks and check sugar levels

Detailed Answer:
Hi Sir, in such case, stop Galvus Met50/500 and continue only with Zoryl M2 morning and evening for two weeks. Check sugar levels. If fasting and post prandial(2 hours after food) are in normal range, then continue the same.

If there is any rise above normal in sugar levels, then add on metformin, 500 in the afternoon after lunch.

Thank you sir.

Above answer was peer-reviewed by : Dr. Priyanka G Raj