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What Causes Lump Above The Site Of Morphine Pump Insertion?
Question: Since 1993, I have had 13 major lower back surgeries with no results. 14 years ago I had a morphine pump put in near my right side and a cat hater put in by my spine just above the damage. I had a to replace my pump 3 years ago due to low battery. I had started to notice a lump on top of this pump which started about a month ago. I had a third pump put in and the other one taken out. The physician found a build up of morphine on all my organs and a buildup about size of a soft ball around it. They found my cat hater had a split in it causing the morphine to leak apparently since my first pump was put in. I had been receiving a large dose of morphine each month since than. The physician doing my last surgery scraped out as much buildup without injuring any of my organs. My question is; will my body get rid of what is still there? I am 68 years old.
Brief Answer:
Naloxane is the antidote
Detailed Answer:
Hey thanks for your faith in the health care Magic
I have gone through your question and I understood your problem.
First understand the kinetics behind morphine metabolism. A typical serum half life for morphine is about 3 hours give or take an hour with normal liver and urinary function. If a new dose is given at the halflife interval, ie 3 hours the build up is like this; 1 + 1/2 + 1/4 + 1/8 + 1/16 ... reaching a limit of approximately 2x the serum level of the individual dose. The body increases accommodation daily.
Now coming back to your question. Its highly impossible to get rid of it completely but we can try reducing its effects by medical therapy. Naloxane is the widely used drug for this.
It’s usually given intravenously, as this is the quickest way to get the medication into the bloodstream. It can also be given subcutaneously, or intramuscularly. It has been found very effective.
But it should only be used under close medical supervision.
I hope my answer was helpful for you . Dont forget to close the discussion.Thank you.
DR . XXXXXXX HASABE
Naloxane is the antidote
Detailed Answer:
Hey thanks for your faith in the health care Magic
I have gone through your question and I understood your problem.
First understand the kinetics behind morphine metabolism. A typical serum half life for morphine is about 3 hours give or take an hour with normal liver and urinary function. If a new dose is given at the halflife interval, ie 3 hours the build up is like this; 1 + 1/2 + 1/4 + 1/8 + 1/16 ... reaching a limit of approximately 2x the serum level of the individual dose. The body increases accommodation daily.
Now coming back to your question. Its highly impossible to get rid of it completely but we can try reducing its effects by medical therapy. Naloxane is the widely used drug for this.
It’s usually given intravenously, as this is the quickest way to get the medication into the bloodstream. It can also be given subcutaneously, or intramuscularly. It has been found very effective.
But it should only be used under close medical supervision.
I hope my answer was helpful for you . Dont forget to close the discussion.Thank you.
DR . XXXXXXX HASABE
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Above answer was peer-reviewed by :
Dr. Shanthi.E
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