What Causes Muscle Weakness And Rubbing Of Bone Joints Against Each Other?

Posted on Thu, 12 Mar 2015

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Thu, 12 Mar 2015 Answered on

Thu, 2 Apr 2015 Last reviewed on

Question : The major bone joints in my body are rubbing against each other also the muscles are getting very weak. feeling some unknown illness which is unable to express. All tests are done. i.e X RAYS, MRI and some blood tests. They all shows nothing abnormality. BUT I am feeling 100 % abnormality. The Doctor has also agreed some abnormality in my body which cannot be traced out with those tests. Finally he refers Tissue fluid culture test and later biopsy of a muscle. Can u pls explain sir explain about these tests and under what circumstances the tests will be referred. Will the tests provides exact reason of my abnormality.

Answered by Dr. Vaibhav Gandhi (-4 hours later)

Brief Answer:
Explained below

Detailed Answer:
Hello

I have read your query,

Muscle biopsy and tissue culture can be done to rule out diseases like
Myopathy or muscular dystrophy.

Presence of a systemic disorder that may have silent manifestations in muscle for which muscle biopsy can help include,
Immune or Inflammatory disorders
Vasculitis,Microvasculopathies
Sarcoidosis ,Amyloid

Neoplasm: Angiotropic lymphoma; Adenocarcinoma
Mitochondrial disorders
Myasthenia gravis
Myotonias

Tissue fluid culture test is done to see for any organism growing in tissue and it’s sensitive to particular medicine.

If there is muscle tissue disorder or disease due to micro-organism then your abnormality can be detected by these tests.

Hope this answers your query. If you have additional questions or follow up queries then please do not hesitate in writing to us. I will be happy to answer your queries.

Wishing you good health.

Take care.

Above answer was peer-reviewed by : Dr. Pradeep Vitta

Follow up: Dr. Vaibhav Gandhi (7 hours later)

HOW TISSUE FLUID CULTURE TEST WILL BE DONE. IS IT A SURGERY

Answered by Dr. Vaibhav Gandhi (15 hours later)

Brief Answer:
Explained below

Detailed Answer:
Hello again,

Tissue fluid culture test is done under local anaesthesia with help of image guided radiology.
This is not surgery.

Hope this answers your query. If you have additional questions or follow up queries then please do not hesitate in writing to us. I will be happy to answer your queries.

Wishing you good health.

Take care

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar