What Causes Pitting Edema Of Left Foot And Ankle When On Amlodipine?

Posted on Tue, 25 Mar 2014

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Tue, 25 Mar 2014 Answered on

Mon, 14 Apr 2014 Last reviewed on

Question : Hello Dr. I am a 74 y.o. female - active and healthy. Approx., one year ago I developed hypertension and it has been controlled well with Amlodipine 7.5 mg. Take cylexia for Fibromyalgia, and have mild asthma - no prob. unless I develop a cold. Current Problem. about 3 weeks ago - I suddenly developed pitting edema of left foot and ankle only. no pain- no limitation in movement or walking. no edema of rt. foot is noted.

Answered by Dr. Lohit K (1 hour later)

Brief Answer: amlodepine may cause? organ system or local proble Detailed Answer: Hi, thanks for using HCM. I went through the query and understood your concern. Since there is no limitations of movement, no pain or tenderness and no signs of inflammation, the probable cause for pitting edema at ankle and knee joint may be amlodepine. This drug has been known to cause edema. So with your doctor's advice you can reduce the dose to 5mg with monitoring BP and can shift to other drugs like telmisartan or losartan (ARB) which ore devoid of this side effect. The other causes for this problem may be any injury or infection in limb or other any organ system problem like liver, kidney or anaemia. You can get done blood test to ruleout these problem. I hope this information helps you. Feel free to ask if any further queries and I will be glad to answer them. Wish you good health and faster recovery. Regards

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar