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What Causes Recurrent Miscarriages?
Question: Recurrent miscarriages:
I had 3 miscarriages in the past 2 yrs. The reasons not known. I feel the hospitals I went for were too commercialized with no personal care. I am expecting some tests to be suggested to find out the cause of these losses. I have got a Torch test done twice and little bit worried as Dr are saying I have infection based on UIgg values. Is a higher positive value a matter of concern. I do not want to go for un necessary medications.
I had 3 miscarriages in the past 2 yrs. The reasons not known. I feel the hospitals I went for were too commercialized with no personal care. I am expecting some tests to be suggested to find out the cause of these losses. I have got a Torch test done twice and little bit worried as Dr are saying I have infection based on UIgg values. Is a higher positive value a matter of concern. I do not want to go for un necessary medications.
Brief Answer:
NO NEED FOR DRUGS FOR RAISED IG G LEVELS
Detailed Answer:
Hello
Thanks for writing to us with your health concern.
First and foremost - raised Ig G levels need no treatment.
They just indicate past infection, and a high Ig G level indicates that you have acquired immunity against that infection, could be due to vaccination or past exposure.
Only a high Ig M level means that the infection is recent and still active, and needs to be treated.
In your case, there is no active or current infection, and you need no treatment for your TORCH reports.
That said, let me guide you a bit more regarding conception related issues.
First, do not try to conceive now, your last miscarriage was in July, wait for atleast 3 months.
In that time period, take daily 5 mg per day folic acid tablets.
What is your height and weight ?
If you have any stress, anxiety, late nights, erratic eating habits etc, then correct those factors.
For recurrent pregnancy losses, the following list of investigations is advised, I am writing them down as a checklist so that you can compare what tests have been done and what part of the investigative workup is still remaining.
1. Complete blood count , blood group and typing, and viral markers - HIV, HBsAg, HCV for both partners. (Why was your Indirect Coombs test done ? )
2. Thyroid function tests.
3. Chromosomal analysis of each aborted tissue, this is most important.
4. Karyotype of both parents.
5. LAC, ACA, APLA ( Antiphospholipid antibody testing ), coagulation profile, Homocysteine level, Protein C, Protein S, Factor V Leiden mutation testing.
6. Your blood pressure, height and weight.
7. Semen analysis and semen culture of husband.
8. A basic transvaginal ultrasound scan on day 2 of your cycle.
9. AMH values to assess your egg forming capacity.
ONce this workup is done, as advised earlier in this answer, wait for 3 months .
Then you can safely try to conceive.
Once you skip your period, get pregnancy testing at the earliest.
Also, get early pregnancy scanning at 6 weeks to check for the cardiac activity in the fetus.
As soon as pregnancy is confirmed, you should be put on the following medications - low dose aspirin, injectable heparin, folic acid and progesterone.
This heavy pregnancy support is essential to prevent future miscarriages.
All the best
Please feel free to discuss further.
Wish you good luck always.
NO NEED FOR DRUGS FOR RAISED IG G LEVELS
Detailed Answer:
Hello
Thanks for writing to us with your health concern.
First and foremost - raised Ig G levels need no treatment.
They just indicate past infection, and a high Ig G level indicates that you have acquired immunity against that infection, could be due to vaccination or past exposure.
Only a high Ig M level means that the infection is recent and still active, and needs to be treated.
In your case, there is no active or current infection, and you need no treatment for your TORCH reports.
That said, let me guide you a bit more regarding conception related issues.
First, do not try to conceive now, your last miscarriage was in July, wait for atleast 3 months.
In that time period, take daily 5 mg per day folic acid tablets.
What is your height and weight ?
If you have any stress, anxiety, late nights, erratic eating habits etc, then correct those factors.
For recurrent pregnancy losses, the following list of investigations is advised, I am writing them down as a checklist so that you can compare what tests have been done and what part of the investigative workup is still remaining.
1. Complete blood count , blood group and typing, and viral markers - HIV, HBsAg, HCV for both partners. (Why was your Indirect Coombs test done ? )
2. Thyroid function tests.
3. Chromosomal analysis of each aborted tissue, this is most important.
4. Karyotype of both parents.
5. LAC, ACA, APLA ( Antiphospholipid antibody testing ), coagulation profile, Homocysteine level, Protein C, Protein S, Factor V Leiden mutation testing.
6. Your blood pressure, height and weight.
7. Semen analysis and semen culture of husband.
8. A basic transvaginal ultrasound scan on day 2 of your cycle.
9. AMH values to assess your egg forming capacity.
ONce this workup is done, as advised earlier in this answer, wait for 3 months .
Then you can safely try to conceive.
Once you skip your period, get pregnancy testing at the earliest.
Also, get early pregnancy scanning at 6 weeks to check for the cardiac activity in the fetus.
As soon as pregnancy is confirmed, you should be put on the following medications - low dose aspirin, injectable heparin, folic acid and progesterone.
This heavy pregnancy support is essential to prevent future miscarriages.
All the best
Please feel free to discuss further.
Wish you good luck always.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Answered by
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