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What Causes Recurring Skin Rashes All Over Body And Bruising On Palms?

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Posted on Wed, 18 Mar 2015
Question: Hi Doctor,
My mother has developed skin rashes on her body and this is the third time in 7 months. Even her palms have bruises. She is an acute asthma patient from birth and also has diabetes/high BP since 5 years. We went to skin specialist and he has suggested Absolute Eosinophil Count investigation which is attached. The count is 901 cells/cumm which is drastically out of range. Please help us with possible issues because of the high Abs Eosinophil count and any further investigations if required.
doctor
Answered by Dr. S. Samanta (32 minutes later)
Brief Answer:
SHE NEEDS SOME MORE INVESTIGATIONS / TESTS

Detailed Answer:
Dear Madam,

Thanks for sharing your mother's health concerns with us!

After going through your description and the report attached herewith, I may summarize as follows:

1. she has generalised skin rashes which is recurrent and frequent but treatment history is not there; palms are not spared!

2. she has been suffering from bronchial asthma since childhood and I assume that it is well controlled except some acute episodes

3. she also suffers from high blood sugar and high blood pressure; possibly well controlled!

4. her recent blood absolute eosinophil count (AEC) is 901 against normal value of 40-440; which is very high; no previous record;

Therefore, her high AEC could be related to:

1. asthma/allergic coughs/hay fever

2. allergic type of dermatitis: eczematous, atopic, contact type etc..

3. aspergillosis may be in some old cavity in the lungs

4. worm infestation

5. drug allergies

6. various eosinophilic inflammations or malignancies

I don't think that it is related to diabetes or blood pressure but could be due to some drug allergies!

Therefore, to be more specific, she needs:

1. a skin biopsy

2. complete blood counts

3. serum IgE level

4. chest x-ray

5. allergy tests

6. stool examination

You should consider talking about the aforementioned tests with your treating doctor.

Please do not hesitate to write to me if any more clarification is required; regards,


Above answer was peer-reviewed by : Dr. Prasad
doctor
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Follow up: Dr. S. Samanta (50 minutes later)
She has acute asthma and now she is everyday using Philips Respitronics at nights due to sleepnemia. It was observed during the tests that in the sleep, my mother sometimes has breathing stopped for 17 seconds. Her asthma is in control but she cannot walk continuously for atleast 2 mins. Blood sugar and BP are in control. Is this related to any type of cancer or Leukemia because you have suggested skin biopsy? I am afraid after going through few sites.

I hope AEC of 931 is mild but is it severe in any form? We will try to make her undergo the tests prescribed by you after talking to the doctor we are dealing with here.
doctor
Answered by Dr. S. Samanta (9 hours later)
Brief Answer:
TESTS ARE TO BE DONE ONLY AFTER ASKING HER DOCTOR!

Detailed Answer:
Dear Madam,

In asthma, chronic medicine-takers or skin allergies this kind of high eosinophil count is common and it is moderate; not severe also but it should be considered in the clinical context; I mean her previous records and present symptoms....

As she is having some problems, this count is likely to rise and should be taken seriously as this could be an indicator of her disease status!

She must continue the medicines prescribed by your doctor and skin biopsy is advised just to see if any kind of panniculitis-like skin lymphoma lesion is there or it is just allergic pathology!

In short:

1. she needs the tests to see the association of AEC with skin lesions if any and medications are to be continued

2. all the tests should be undergone only after discussion with her treating physician as s/he knows the clinical status as well as the the nature of the skin lesions!

regards,
Note: Do you have more questions on diagnosis or treatment of blood disorders? Ask An Expert/ Specialist Now

Above answer was peer-reviewed by : Dr. Shanthi.E
doctor
Answered by
Dr.
Dr. S. Samanta

Pathologist and Microbiologist

Practicing since :2004

Answered : 1107 Questions

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What Causes Recurring Skin Rashes All Over Body And Bruising On Palms?

Brief Answer: SHE NEEDS SOME MORE INVESTIGATIONS / TESTS Detailed Answer: Dear Madam, Thanks for sharing your mother's health concerns with us! After going through your description and the report attached herewith, I may summarize as follows: 1. she has generalised skin rashes which is recurrent and frequent but treatment history is not there; palms are not spared! 2. she has been suffering from bronchial asthma since childhood and I assume that it is well controlled except some acute episodes 3. she also suffers from high blood sugar and high blood pressure; possibly well controlled! 4. her recent blood absolute eosinophil count (AEC) is 901 against normal value of 40-440; which is very high; no previous record; Therefore, her high AEC could be related to: 1. asthma/allergic coughs/hay fever 2. allergic type of dermatitis: eczematous, atopic, contact type etc.. 3. aspergillosis may be in some old cavity in the lungs 4. worm infestation 5. drug allergies 6. various eosinophilic inflammations or malignancies I don't think that it is related to diabetes or blood pressure but could be due to some drug allergies! Therefore, to be more specific, she needs: 1. a skin biopsy 2. complete blood counts 3. serum IgE level 4. chest x-ray 5. allergy tests 6. stool examination You should consider talking about the aforementioned tests with your treating doctor. Please do not hesitate to write to me if any more clarification is required; regards,