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What Causes Redness On The Lower Legs While On Methotrexate?

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Posted on Wed, 14 Jun 2017
Question: Both of my lower legs have a redness look. Is this caused by RA?
I am on methotrexate (7) once a week. Any connection?
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Answered by Dr. T Chandrakant (2 hours later)
Brief Answer:
Can cause

Detailed Answer:
Hi.
Thanks for your query, albeit short and specific.
To recapitulate: Female/83 - on Methotrexate once a week - redness look in both lower legs - wants to know whether by RA or Methotrexate...

Methotrexate is known to cause reddening of the skin.
RA itself does not cause skin rash - it causes nodule and vasculitis but the skin rash can be enhanced if some medicines are also taken one of these are Metrotrexate, although this occurs rarely. Other medicines which are like Ibuprofen taken for pain.

Please post clear and focused photographs as these help sometimes for on-the-spot diagnosis.
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Above answer was peer-reviewed by : Dr. Vaishalee Punj
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Dr. T Chandrakant

General Surgeon

Practicing since :1984

Answered : 19782 Questions

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What Causes Redness On The Lower Legs While On Methotrexate?

Brief Answer: Can cause Detailed Answer: Hi. Thanks for your query, albeit short and specific. To recapitulate: Female/83 - on Methotrexate once a week - redness look in both lower legs - wants to know whether by RA or Methotrexate... Methotrexate is known to cause reddening of the skin. RA itself does not cause skin rash - it causes nodule and vasculitis but the skin rash can be enhanced if some medicines are also taken one of these are Metrotrexate, although this occurs rarely. Other medicines which are like Ibuprofen taken for pain. Please post clear and focused photographs as these help sometimes for on-the-spot diagnosis.