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What Causes Septum Primum ASD During Pregnancy?

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Posted on Thu, 3 Apr 2014
Question: Hello, I am 28 weeks pregnant with my first child. The perinatologist found a possible septum primum ASD on ultrasound at 25 weeks. I also saw a fetal cardiologist to confirm, but she was unable to confirm yet as the baby's spine was causing too much shadowing. I see her and the perinatologist next week for a repeat echo. They recommended a MaterniT21 test, which was negative for Down Syndrome, and negative for all other screens. My question is if there is an ASD, if my drinking alcohol before I knew I was pregnant could have anything to do with it. It was an unplanned pregnancy, and before I found out right at about 2-3 weeks post conception, I had 3-4 glasses of wine most nights. I immediately stopped after the positive pregnancy test. Also, I was wondering if alcohol this early in the pregnancy could have caused other problems. Everything else on the 20 week ultrasound appeared normal, so I just want to be reassured that everything is okay. I understand any effects on the developing brain would have occurred with continued drinking later than 2-3 weeks post conception? With the brain measurements all appearing normal, and the corpus callosum intact, is it unlikely that there is any mental damage done that early? Also, what is the likelihood of any signs of FAS with the above scenario? Or is it most likely an isolated possible heart defect. Second question, I have just started feeling short of breath as the baby is starting to push up on my diaphragm. And have also had a bad cold this last week. I am definitely having trouble sleeping at night due to breathing issues, and anxiety of feeling like I'm suffocating. I have pretty much avoided all meds throughout the pregnancy, whether they are considered safe or not until this last week, I took some sudafed, and maybe up to 2 benadryl tabs at night. How safe do you consider sudafed and benadryl at the start of the third trimester? Should I try to limit the time to two weeks if needed for insomnia, or is it really and truly safe in your opinion? Thank you!
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Answered by Dr. Aarti Abraham (1 hour later)
Brief Answer: EXPLAINED BELOW Detailed Answer: Hello Thanks for writing to us with your health concern. I am Dr. Abraham , OB - GYN , and will be glad to assist you with the query posted. Let me deal with it in two parts as you have written in. 1. Can you please upload the ultrasound scan report, that will enable me to formulate a more specific opinion as opposed to just a single line regarding the ASD. A septum primum defect is generally associated with more complex cardiac anomalies, as opposed to a septum secundum defect, which is generally more benign. However , without any details of the defect, it is difficult to be specific. Yes, alcohol intake during pregnancy is associated with heart defects, so this could be a causal relationship. Generally, more than 7 drinks a week ( includes wine ) is known to induce the negative effects. You did cross this limit. The good news is that when this intake happens during the very initial few days, before your period is due, then the effects are less drastic . If you continue the drinking during the first trimester, chances of FAS are higher. This is not true in your case, also the scanning and Trisomy 21 screen are negative, so you can be further reassured. The structural brain scan also seems normal, however , alcohol effects include behavioural problems in the baby, but once again, this is seen more often with maternal alcohol intake later than 2 - 3 weeks post conception. 2. With the onset of the third trimester, breathing issues are majorly exacerbated due to the pressure exerted by the growing baby. Sudafed is pregnancy category C, while benadryl is pregnancy category B, so if you have to, use Benadryl. Both these drugs are relatively safer in the third trimester, when most organ systems are fully functional, and are contraindicated in the first trimester as a rule. You can use them for symptomatic relief, consider using plain saline nasal drops to relieve the congestion. All the best Please feel free to discuss further.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Aarti Abraham

OBGYN

Practicing since :1998

Answered : 6004 Questions

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What Causes Septum Primum ASD During Pregnancy?

Brief Answer: EXPLAINED BELOW Detailed Answer: Hello Thanks for writing to us with your health concern. I am Dr. Abraham , OB - GYN , and will be glad to assist you with the query posted. Let me deal with it in two parts as you have written in. 1. Can you please upload the ultrasound scan report, that will enable me to formulate a more specific opinion as opposed to just a single line regarding the ASD. A septum primum defect is generally associated with more complex cardiac anomalies, as opposed to a septum secundum defect, which is generally more benign. However , without any details of the defect, it is difficult to be specific. Yes, alcohol intake during pregnancy is associated with heart defects, so this could be a causal relationship. Generally, more than 7 drinks a week ( includes wine ) is known to induce the negative effects. You did cross this limit. The good news is that when this intake happens during the very initial few days, before your period is due, then the effects are less drastic . If you continue the drinking during the first trimester, chances of FAS are higher. This is not true in your case, also the scanning and Trisomy 21 screen are negative, so you can be further reassured. The structural brain scan also seems normal, however , alcohol effects include behavioural problems in the baby, but once again, this is seen more often with maternal alcohol intake later than 2 - 3 weeks post conception. 2. With the onset of the third trimester, breathing issues are majorly exacerbated due to the pressure exerted by the growing baby. Sudafed is pregnancy category C, while benadryl is pregnancy category B, so if you have to, use Benadryl. Both these drugs are relatively safer in the third trimester, when most organ systems are fully functional, and are contraindicated in the first trimester as a rule. You can use them for symptomatic relief, consider using plain saline nasal drops to relieve the congestion. All the best Please feel free to discuss further.