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What Causes Swelling Of The Legs When Suffering From Thyroid Problem?

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Posted on Sun, 30 Mar 2014
Twitter Sun, 30 Mar 2014 Answered on
Twitter Mon, 21 Apr 2014 Last reviewed on
Question : I was originally diagnosed 75mcg levothyroxine for my hypothyroid. After 2 years I felt that it made me anxious w/insomnia. Without doctor approval or labs, I cut dose in half. Two months into 1/2 dose, I started getting ankle and leg swelling-hard non-pitting. Found out here that I should not have done and went back on full dose of 75mcg on 3/15/2014-15 days ago. Now, I am insomnia again. The swelling improved after a week, then yesterday hard swelling and now redness and burning in feet. I this now a symptom of hypothyroid, hyperthyroid or just IMBALANCE of thyroid levels in general? Thanks.
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Answered by Dr. Shehzad Topiwala (4 hours later)
Brief Answer: Thyroid Detailed Answer: Swelling of the legs can be a symptom of an underactive thyroid but redness and burning is not known to be associated with either (hyper nor hypo). It is also not advisable to arbitrarily change doses of the thyroid medication like this as it causes major fluctuations in the blood levels. This is not desirable. Furthermore, it is important to know if you truly have hypothyroidism. Have you ever had thyroid auto antibodies like anti TPO (Thyroid peroxidase) and/or anti Thyroglobulin antibodies tested? And if so, were any one them positive? Further do you recall your baseline TSH levels? Were they above 4 ? If the diagnosis is correct them you should be on steady doses that keep your TSH between 0.4 and 2.5 most of the time for optimal thyroid health.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Follow up: Dr. Shehzad Topiwala (1 hour later)
I know that I should not have messed with my original dose. I believe this is caused all the issues. My original TSH level was 4.50 I believe or around there. The doctor immediately put me on 75mcg - he did not take the dose up slowly. At that time I experienced lots of night sweats, anxiety, irritability, aggressive - quickly to argue, slightly swollen hands and face. I called and he stated that it was my body adjusting to the Levothyroxine. Having both testing I have had at annual physicals shows my thyroid at normal levels now. But still having the other symptoms, I chose myself to take my dose down as you can see from my comment. Then when I was told my Dr. XXXXXXX who confirmed your diagnosis, I went back to original 75mcg. It seem to help in the first week. Now the last two days, I have same type of swelling and burning-just woke up after 8 hours sleep and the symptoms are completely gone - feet look normal. But I am sure that as I am up, I will experience the symptoms again. Can you please tell me the best tests that I can have my doctor run to determine a good level for my thyroid? Thanks.
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Answered by Dr. Shehzad Topiwala (2 hours later)
Brief Answer: Follow up Detailed Answer: TSH Free T4 Anti TPO antibodies Anti Thyroglobulin antibodies
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Dr. Shehzad Topiwala

Endocrinologist

Practicing since :2001

Answered : 1663 Questions

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What Causes Swelling Of The Legs When Suffering From Thyroid Problem?

Brief Answer: Thyroid Detailed Answer: Swelling of the legs can be a symptom of an underactive thyroid but redness and burning is not known to be associated with either (hyper nor hypo). It is also not advisable to arbitrarily change doses of the thyroid medication like this as it causes major fluctuations in the blood levels. This is not desirable. Furthermore, it is important to know if you truly have hypothyroidism. Have you ever had thyroid auto antibodies like anti TPO (Thyroid peroxidase) and/or anti Thyroglobulin antibodies tested? And if so, were any one them positive? Further do you recall your baseline TSH levels? Were they above 4 ? If the diagnosis is correct them you should be on steady doses that keep your TSH between 0.4 and 2.5 most of the time for optimal thyroid health.