What Causes Testicular Atrophy?

Posted on Tue, 11 Apr 2017

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Tue, 11 Apr 2017 Answered on

Thu, 4 May 2017 Last reviewed on

Question : Below are test results. Kindly advise further, any treatment possible ?
FSH 8.06, LH 8.24, PROLATIN 5.4, TESTOSETRONE 364.7
Semen Analysis showed No Sperm Count.
Testicular FNAC
Giemsa stains smears from both sides are of low cellularity with few short and stout. Only sertoli cells seen in predominant single form and ocassionally in small groups. No spermatogenic cells seen. Suggestive of Testicular Atrophy

Answered by Dr. Khushboo Priya (1 hour later)

Brief Answer:
Focal spermatogenesis may be there.

Detailed Answer:
Hi, I think according to your reports, it may be a sertoli cell only syndrome or atrophic pattern. In this, focal spermatogenesis may be seen. FNAC can't tell the exact architecture of testis. So, it has limitations in diagnosing atrophy. I think you should go for a inhibin B level to predict the success of TESE or Micro TESA. It is a good predictor of that according to various studies. Also do a karyotyping for yourself. Discuss with your doctor regarding this. If no sperms are found on TESE or micro TESA also, you will have to go for a donor sperm.Hope I have answered your question.

Above answer was peer-reviewed by : Dr. Remy Koshy