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What Causes Tingling Sensation In Limbs When Diagnosed With Grave's Disease?

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Posted on Mon, 21 Sep 2015
Question: I have graves disease and am being treated with low dose tapazole. I take 5 mg a day. i am having a strange sensation in my arms and hands. My skin feels tight and it is tingling in my arms, hands and fingers. Is this normal?
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Answered by Dr. Shehzad Topiwala (1 hour later)
Brief Answer:
Graves; Tapazole

Detailed Answer:
Sorry to note your symptoms. They don't seem normal.
It is possible they may be a side effect of the tapazole which can occasionally cause skin and nerve problems.
When I see someone like you in my practice , I ask them to consider stopping the tapazole for a week or so, in order to observe if the symptoms go away. If they do, it is possible they are from tapazole. Upon restarting tapazole then, if they re-occur then it is very likely they are due to tapazole.

But I offer this trial to only those whose Graves is well controlled. Otherwise, stopping the tapazole is dangerous. So you may wish to see an endocrinologist in person who will have the opportunity to thoroughly examine you and with whom you can stay in regular touch with.

There is an alternative medication for Graves which can be taken instead of tapazole. It is called PTU (Propyl thio uracil). However it is now generally not recommended due to a risk of serious liver problems. It can cause the same skin and nerve problems too because it is in the same category as tapazole. But sometimes medication side effects are specific to one molecule.
Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Shehzad Topiwala

Endocrinologist

Practicing since :2001

Answered : 1663 Questions

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What Causes Tingling Sensation In Limbs When Diagnosed With Grave's Disease?

Brief Answer: Graves; Tapazole Detailed Answer: Sorry to note your symptoms. They don't seem normal. It is possible they may be a side effect of the tapazole which can occasionally cause skin and nerve problems. When I see someone like you in my practice , I ask them to consider stopping the tapazole for a week or so, in order to observe if the symptoms go away. If they do, it is possible they are from tapazole. Upon restarting tapazole then, if they re-occur then it is very likely they are due to tapazole. But I offer this trial to only those whose Graves is well controlled. Otherwise, stopping the tapazole is dangerous. So you may wish to see an endocrinologist in person who will have the opportunity to thoroughly examine you and with whom you can stay in regular touch with. There is an alternative medication for Graves which can be taken instead of tapazole. It is called PTU (Propyl thio uracil). However it is now generally not recommended due to a risk of serious liver problems. It can cause the same skin and nerve problems too because it is in the same category as tapazole. But sometimes medication side effects are specific to one molecule.