What Could Be The Reason For Very High Beta HCG Values Compared To The Reference Range?

Posted on Tue, 10 Jul 2018

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Tue, 10 Jul 2018 Answered on

Mon, 11 Jul 2022 Last reviewed on

Question : Hello Doctor,

Could you please let us know your views / observations about the current status of my wife's reports

Age: 31 yrs 10 months
LMP: 02 XXXXXXX 2018
UPT: Positive (on 07 July 2018)

Beta HCG: 148089 mIU/mL (07 July 2018, 03:15 pm)
Beta HCG: 221085 mIU/mL (09 July 2018, 03:15 pm)

Reports attached for the above two readings.

Beta HCG values seems to be very high compared to the reference range . What could be the reason? Is this of a concern?
The rate of growth in 48 hours is roughly 50%, which seems to be less than the expected normal growth. What could be the possible reasons?

Please let us know in case of any complications.

Thanks in advance,

Best Regards,

Answered by Dr. Deepti Verma (25 minutes later)

Brief Answer:
Transvaginal ultrasound advised

Detailed Answer:

Hi,

Beta hCG values are normal for a 5-6 weeks pregnancy which was the gestational period at the time of sampling.
However, the beta hCG levels should double in 48 hours.
If the increase is less than 65%, then it can be a ectopic pregnancy.

A transvaginal ultrasound is advised tomorrow to confirm the location and timing of the pregnancy.

Hope you found the answer helpful.
Regards,
Dr. Deepti Verma
OBGYN
Maternal and fetal medicine specialist

Above answer was peer-reviewed by : Dr. Nagamani Ng