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What Do Elevated TSH Levels And Following Ultrasound Reports Indicate?

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Posted on Thu, 30 Mar 2017
Twitter Thu, 30 Mar 2017 Answered on
Twitter Thu, 20 Apr 2017 Last reviewed on
Question : HI
I recently had an elevated TSH at 11.6. My thyroid ultrasound reports states " mid thyroid lobe measuring 1.5x1.6x1.1cm, which is echogenic with a hypochoic halo and internal cystic area. there is a lobulated collection of diminished echogenicity in the anterior aspect of the right mid thyroid lobe measuring 1.4x2.0x0.7cm. There is a hypochoic mass in the right side of the isthmus measuring 1.2x0.3x0.8 cm.
doctor
Answered by Dr. Shehzad Topiwala (26 minutes later)
Brief Answer:
Thyroid

Detailed Answer:
Considering you are on levo thyroxine, it is likely you have chronic Hashimoto's thyroiditis. This is the name for a medical condition that typically leads to a permanently under-active thyroid state called Hypothyroidism. So if your diagnosis is correct, then you are on the right treatment for this condition.

Notably, in this type of hypothyroidism, often the thyroid gland appears to have nodules when in reality there are none. This has been well described in medical literature as 'Pseudo-nodules' implying that these mislead the ultrasound technician or radiologist to believe there are lumps in the thyroid gland. So one has to be careful while interpreting the thyroid ultrasound in this situation.
If indeed nodules are actually present then they need to be further characterized in terms of borders, calcifications, vascularity etc in addition to the description you have been provided. It is helpful to decide whether or nor to proceed with biopsy. The latter is also known as FNA (Fine Needle Aspiration).
Moreover the decision for FNA will also depend on a thorough assessment by an endocrinologist in-person because a detailed neck check is necessary.
When I see someone like you in my practice, I tend to increase the levo thyroxine dose by 25 mcg , and then 6 weeks later I typically order the following blood tests in addition to a detailed physical examination:

CBC (Complete Blood Count, also known as Hemogram; includes Hemoglobin, WBC and Platelet counts)
Electrolytes (Sodium and Potassium in particular)
HbA1c (Glycosylated Hemoglobin = your last 3 months' glucose average). Also known by other names such as GlycoHemoglobin or Glycated Hemoglobin or A1c
Liver function tests (SGOT , SGPT, Albumin, Bilirubin, Alkaline Phosphatase)
Kidney function tests (BUN, Creatinine)
TSH (checks your thyroid)
Free T4 (this too checks your thyroid) Thyroid autoantibodies : Anti Thyroid Peroxidase (TPO) antibodies and Anti Thyroglobulin antibodies
25 hydroxy Vitamin D levels (ideal range 40 to 60 ng/ml = 100 to 150 nmol/liter)

None of these tests require any fasting and can be done at any time of the day Correct diagnosis and treatment requires the opportunity to examine the patient so you must see an endocrinologist in-person.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Shehzad Topiwala (16 minutes later)
I am scheduled to see an endocrine surgeon in 2 weeks for a biopsy and consultation.
doctor
Answered by Dr. Shehzad Topiwala (26 hours later)
Brief Answer:
Follow up

Detailed Answer:
Noted.
Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Shehzad Topiwala

Endocrinologist

Practicing since :2001

Answered : 1663 Questions

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What Do Elevated TSH Levels And Following Ultrasound Reports Indicate?

Brief Answer: Thyroid Detailed Answer: Considering you are on levo thyroxine, it is likely you have chronic Hashimoto's thyroiditis. This is the name for a medical condition that typically leads to a permanently under-active thyroid state called Hypothyroidism. So if your diagnosis is correct, then you are on the right treatment for this condition. Notably, in this type of hypothyroidism, often the thyroid gland appears to have nodules when in reality there are none. This has been well described in medical literature as 'Pseudo-nodules' implying that these mislead the ultrasound technician or radiologist to believe there are lumps in the thyroid gland. So one has to be careful while interpreting the thyroid ultrasound in this situation. If indeed nodules are actually present then they need to be further characterized in terms of borders, calcifications, vascularity etc in addition to the description you have been provided. It is helpful to decide whether or nor to proceed with biopsy. The latter is also known as FNA (Fine Needle Aspiration). Moreover the decision for FNA will also depend on a thorough assessment by an endocrinologist in-person because a detailed neck check is necessary. When I see someone like you in my practice, I tend to increase the levo thyroxine dose by 25 mcg , and then 6 weeks later I typically order the following blood tests in addition to a detailed physical examination: CBC (Complete Blood Count, also known as Hemogram; includes Hemoglobin, WBC and Platelet counts) Electrolytes (Sodium and Potassium in particular) HbA1c (Glycosylated Hemoglobin = your last 3 months' glucose average). Also known by other names such as GlycoHemoglobin or Glycated Hemoglobin or A1c Liver function tests (SGOT , SGPT, Albumin, Bilirubin, Alkaline Phosphatase) Kidney function tests (BUN, Creatinine) TSH (checks your thyroid) Free T4 (this too checks your thyroid) Thyroid autoantibodies : Anti Thyroid Peroxidase (TPO) antibodies and Anti Thyroglobulin antibodies 25 hydroxy Vitamin D levels (ideal range 40 to 60 ng/ml = 100 to 150 nmol/liter) None of these tests require any fasting and can be done at any time of the day Correct diagnosis and treatment requires the opportunity to examine the patient so you must see an endocrinologist in-person.