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What Do My Lab Test Reports Indicate?

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Posted on Fri, 1 Apr 2016
Twitter Fri, 1 Apr 2016 Answered on
Twitter Fri, 3 Jun 2016 Last reviewed on
Question : Need a second oppinion on this. My primary care dr said neither test is abnormal that both results are still "normal" and just slightly off means nothing
doctor
Answered by Dr. Shehzad Topiwala (1 hour later)
Brief Answer:
Hormone tests

Detailed Answer:
I have reviewed the attached laboratory results.

Your doctor is not grossly wrong in that comment.

Insulin levels can be hard to interpret by themselves. The ideal way to understand what it implies is to check it along with Blood Glucose concentrations. A more complex method is to estimate the HOMA IR ('Homeostasis Model Assessment - Insulin Resistance).
These tools give a better idea about the body's glucose handling and metabolism than a single Insulin level alone.
Yet it is ordered occasionally by doctors. Sometimes when it is severely elevated it might be helpful in indirectly suggesting the possibility of Polycystic Ovarian Syndrome.

The DHEAS is also only slightly high. This does not represent a problem. If it is much higher than this then it indicates the probability of male hormone excess from worrisome causes
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Shehzad Topiwala (8 minutes later)
Here are some more labs. One doctor said nothing wrong another said possible minor pcos. Transvaginal ultrasound normal, ct scan of adrenals normal.
doctor
Answered by Dr. Shehzad Topiwala (23 hours later)
Brief Answer:
Follow up

Detailed Answer:
I have reviewed the additional lab reports.

Bloodwork alone does not represent the full picture. You will be best served by consulting an Endocrinologist in-person who will have the opportunity to examine you.
One can then determine if these tests are sufficient or if more are necessary such as

17 hydroxy Progesterone
IGF1
Midnight Salivary cortisol

to rule out conditions that may be associated with your other labs, such as CAH (Congenital Adrenal Hyperplasia), Acromegaly and Cushing's syndrome
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Shehzad Topiwala (55 minutes later)
I did and the endo said i have none of those. What could it be or is nothing?
doctor
Answered by Dr. Shehzad Topiwala (2 hours later)
Brief Answer:
Second follow up

Detailed Answer:
It should be monitored periodically.

I suggest you stay in touch with your endocrinologist and follow up regularly to see where it goes.
Often, when it comes to hormones, it is the trend over time that is more meaningful than one-off absolute values.
Perhaps a recheck in 6 months would be useful. But this is also at the discretion of the treating endocrinologist, based on findings on physical examination.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Shehzad Topiwala

Endocrinologist

Practicing since :2001

Answered : 1663 Questions

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What Do My Lab Test Reports Indicate?

Brief Answer: Hormone tests Detailed Answer: I have reviewed the attached laboratory results. Your doctor is not grossly wrong in that comment. Insulin levels can be hard to interpret by themselves. The ideal way to understand what it implies is to check it along with Blood Glucose concentrations. A more complex method is to estimate the HOMA IR ('Homeostasis Model Assessment - Insulin Resistance). These tools give a better idea about the body's glucose handling and metabolism than a single Insulin level alone. Yet it is ordered occasionally by doctors. Sometimes when it is severely elevated it might be helpful in indirectly suggesting the possibility of Polycystic Ovarian Syndrome. The DHEAS is also only slightly high. This does not represent a problem. If it is much higher than this then it indicates the probability of male hormone excess from worrisome causes