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What Do Negative Test Results For ANA And C Reactive Protein Indicate?
Posted on
Tue, 3 Feb 2015
Medically reviewed by
Ask A Doctor - 24x7 Medical Review Team
Tue, 3 Feb 2015
Answered on
Tue, 3 Mar 2015
Last reviewed on
Question : If I have negative ANA, normal C reactive & normal sedimentary blood tests could I still have rheumetoid arthritis?
Brief Answer:
Rheumetoid arthritis
Detailed Answer:
Hi,
Thank you for your query. I can understand your concerns.
Anti-nuclear antibody(ANA) is positive only in 20 to 50 % cases of Rheumetoid arthritis.
Acute phase proteins (C-reactive protein ) and ESR (erythrocyte sedimentation rate) may be normal during remission period.
None of these factors like ANA,C-reactive protein or ESR is included in the criteria for the diagnosis of Rheumetoid arthritis.
Regards
Dr. T.K. Biswas M.D. XXXXXXX
Rheumetoid arthritis
Detailed Answer:
Hi,
Thank you for your query. I can understand your concerns.
Anti-nuclear antibody(ANA) is positive only in 20 to 50 % cases of Rheumetoid arthritis.
Acute phase proteins (C-reactive protein ) and ESR (erythrocyte sedimentation rate) may be normal during remission period.
None of these factors like ANA,C-reactive protein or ESR is included in the criteria for the diagnosis of Rheumetoid arthritis.
Regards
Dr. T.K. Biswas M.D. XXXXXXX
Above answer was peer-reviewed by :
Dr. Yogesh D
What are some symptoms of RA
Brief Answer:
Rheumetoid arthritis.
Detailed Answer:
Hi,
Thank you for your query. I can understand your concerns.
Rheumetoid arthritis:
Early symtoms are non-specific:Fatigue,Weakness,Vague arthralgias,Myalgias, Weight loss,parasthesia,Joint stiffness,Poor appetite.
Subsequent symptoms are :
Morning stiffness (more than one hour ). Movements are restricted especially in the morning.
Articular involvement-onset insidious-chronic symmetrical polyarthritis.
Arthritis involving three or more joint areas .
The joints most commonly involved are:
Any diarthrodial joint may be inflamed. Joints involved are painful,swollen and warm.Classic lesions are in small joints of the hands and feet(MCP,MTP,&PIP joints).
In long standing cases non-articular manifestations of rheumatoid arthritis involves various systems including respiratory,cardiovascular,hematological etc.
Regards
Dr. T.K. Biswas M.D. XXXXXXX
Rheumetoid arthritis.
Detailed Answer:
Hi,
Thank you for your query. I can understand your concerns.
Rheumetoid arthritis:
Early symtoms are non-specific:Fatigue,Weakness,Vague arthralgias,Myalgias, Weight loss,parasthesia,Joint stiffness,Poor appetite.
Subsequent symptoms are :
Morning stiffness (more than one hour ). Movements are restricted especially in the morning.
Articular involvement-onset insidious-chronic symmetrical polyarthritis.
Arthritis involving three or more joint areas .
The joints most commonly involved are:
Any diarthrodial joint may be inflamed. Joints involved are painful,swollen and warm.Classic lesions are in small joints of the hands and feet(MCP,MTP,&PIP joints).
In long standing cases non-articular manifestations of rheumatoid arthritis involves various systems including respiratory,cardiovascular,hematological etc.
Regards
Dr. T.K. Biswas M.D. XXXXXXX
Above answer was peer-reviewed by :
Dr. Bhagyalaxmi Nalaparaju
Answered by
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