What Do Pain And Swelling In The Calf And Knee Indicate?
Investigation is required.
Detailed Answer:
Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice.
Unilateral calf swelling and pain may mean various disorders. One diagnosis that is very worrisome is deep vein thrombosis as it may evolve into pulmonary embolism. Other important diagnoses include rupture of Baker's (popliteal) cyst and local infection (erysipelas, which usually causes high fever). Another thing to keep in mind is that drugs like advil may worsen your renal function so they'd better avoided.
Your best next step is would be to visit the ER and have a doctor check your extremity. An ultrasound scan should be sufficient to diagnose deep vein thrombosis or the ruptured cyst. Erysipelas can be diagnosed by inspection only.
Hope I have answered your query.
Take care
Dr. Panagiotis Zografakis, Internal Medicine Specialist