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What Do These Routine Health Check Up Reports In A Heart Patient Indicate?
Question: My father health is also deteriorating.He suffered stroke 2 months ago and at that time his blood cell count was normal and his wbc count was 7500.Early this month in his routine blood checkup we observed decrease in rbc,wbc and platelet count(4th Aug 2015 report attached).thereafter his doctor asked for repeated check to test his levels further and we performed his test on 12 Aug 2015 in which wbc levels fell further to 2.8 and other levels remain same.We then performed a test 2 days ago on 17 Aug in which his wbc count came back to 3.7 but rbc remained at 3.82 and platelet count was 160000.Today in his test report his wbc have become 3.84 however his platelet fell down to 110000 and rbc fell further(19 Aug 2015).What could be the problem
Brief Answer:
alcohol, folic acid deficiency, myelodysplastic syndrome
Detailed Answer:
Hello,
the hematocrit is fairly OK, unless he had a much higher value in the past. The MCV is an important value in his case. The high value may indicate alcohol abuse, folic acid deficiency or myelodysplastic syndrome particularly if his MCV was much lower in the past. Another potential cause of this blood test result is spleen enlargement and dysfunction but usually there are some characteristic findings on the red blood cells (which are missing here).
So testing his spleen size (ultrasound scan or clinical examination), identifying alcohol abuse and consulting a hematologist regarding the potential for myelodysplastic syndrome is the right strategy for investigation.
If nothing comes out of it, a careful review of his medications may help. You may note changes in the blood count after initiating new drugs for example, or confirm that his old regimen was causing no trouble to him by checking old blood counts.
I hope you find my comments helpful!
You can contact me again, if you'd like any clarification or further information.
Kind Regards!
alcohol, folic acid deficiency, myelodysplastic syndrome
Detailed Answer:
Hello,
the hematocrit is fairly OK, unless he had a much higher value in the past. The MCV is an important value in his case. The high value may indicate alcohol abuse, folic acid deficiency or myelodysplastic syndrome particularly if his MCV was much lower in the past. Another potential cause of this blood test result is spleen enlargement and dysfunction but usually there are some characteristic findings on the red blood cells (which are missing here).
So testing his spleen size (ultrasound scan or clinical examination), identifying alcohol abuse and consulting a hematologist regarding the potential for myelodysplastic syndrome is the right strategy for investigation.
If nothing comes out of it, a careful review of his medications may help. You may note changes in the blood count after initiating new drugs for example, or confirm that his old regimen was causing no trouble to him by checking old blood counts.
I hope you find my comments helpful!
You can contact me again, if you'd like any clarification or further information.
Kind Regards!
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
His Ultrasound revealed no spleen enlargement.No alchohol abuse.His folic acid and B12 levels are normal.
His PCV was 45 % ,MCV was 29.47 and RBC were 4.75 in the past.Could stroke have led to these changes in cell count.Also his observed and corrected ESR was 16mm and 12 mm 2 months ago.Is it possible for him to develop myelodysplastic syndrome in 2 months.
What indicates the possibility of myelodysplastic syndrome
His PCV was 45 % ,MCV was 29.47 and RBC were 4.75 in the past.Could stroke have led to these changes in cell count.Also his observed and corrected ESR was 16mm and 12 mm 2 months ago.Is it possible for him to develop myelodysplastic syndrome in 2 months.
What indicates the possibility of myelodysplastic syndrome
Brief Answer:
MDS causes reduction in RBC, WBC and platelets
Detailed Answer:
29.47 is not possible for MCV. Please check again!
Myelodysplastic syndrome causes a reduction in cell counts which may include the red and white blood cells and the platelets. Usually there is a progressive decline over months or years.
Regarding stroke, there is no real connection with the findings, unless the drugs which were instituted (you haven't mentioned them), caused cell count disorders as a side effect.
MDS causes reduction in RBC, WBC and platelets
Detailed Answer:
29.47 is not possible for MCV. Please check again!
Myelodysplastic syndrome causes a reduction in cell counts which may include the red and white blood cells and the platelets. Usually there is a progressive decline over months or years.
Regarding stroke, there is no real connection with the findings, unless the drugs which were instituted (you haven't mentioned them), caused cell count disorders as a side effect.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
His MCV 2 months back was 94.73.It went high to 108.4 but seems to reduce in his latest reports.
His WBC is now increasing so in such case also does there exist possibility of MDS.
We have been giving him Following medicines-
After Breakfast--->
Arbitel 20 for BP OD
Tegrital 200mg (was stopped a month ago) BD
Strocit 500mg BD
Hosit XT OD
After Dinner ----------->
Deplatt A 150mg OD
Lipicure 40 mg OD
Fenolip 145 mg OD
Homochek
We changed some medicines last week on doctor consultation.New regimen is
After Breakfast ------->
Meganeuron OD
Homocheck OD
SHELCAL HD
Arbitel 20 OD
After Dinner --------->
XARELTO OD
DEPLATT OD
CRESTOR OD
EZEMITIBE OD
His WBC are increasing now so does it still implies that his bone murrow is suppressed.
His WBC is now increasing so in such case also does there exist possibility of MDS.
We have been giving him Following medicines-
After Breakfast--->
Arbitel 20 for BP OD
Tegrital 200mg (was stopped a month ago) BD
Strocit 500mg BD
Hosit XT OD
After Dinner ----------->
Deplatt A 150mg OD
Lipicure 40 mg OD
Fenolip 145 mg OD
Homochek
We changed some medicines last week on doctor consultation.New regimen is
After Breakfast ------->
Meganeuron OD
Homocheck OD
SHELCAL HD
Arbitel 20 OD
After Dinner --------->
XARELTO OD
DEPLATT OD
CRESTOR OD
EZEMITIBE OD
His WBC are increasing now so does it still implies that his bone murrow is suppressed.
Brief Answer:
the drugs could be blamed...
Detailed Answer:
lipitor, crestor and xarelto may cause the red blood cell findings, albeit rarely...
I can't identify any other possible reason with the current data.
Kind Regards!
the drugs could be blamed...
Detailed Answer:
lipitor, crestor and xarelto may cause the red blood cell findings, albeit rarely...
I can't identify any other possible reason with the current data.
Kind Regards!
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
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