What Does A Germinal Center Positive For Bcl-6 And Negative For Bcl-2 Indicate?

Posted on Sun, 28 Jan 2018

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Sun, 28 Jan 2018 Answered on

Mon, 6 Aug 2018 Last reviewed on

Question : What is significance of germinal center positive for Bcl-6 and negative for Bcl-2? Patient has enlarged lymph glands on neck, and necrotic tissue on back of tongue

Answered by Dr. Dr. Esmeralda Sera (29 minutes later)

Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice.

Brief Answer:
BCL

There genes are expressed in Non Hodgkin Lemphoma

They have significant in prognosis and therapy of the disease

Hope I have answered your query. Let me know if I can assist you further.

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Above answer was peer-reviewed by : Dr. Prasad